Although no previous requirements are stablished, it is highly recommended, to ensure a certain guarantee of success, that the student has previously studied General Chemistry and Lab Introduction, and to possess basic knowledge on Physics and Mathematics as well.
To this extent, it is also recommended for the students to have studied and passed Chemical Analysis I.
JUSTIFICATION IN THE CURRICULUM:
The Pharmacist, as a health professional at the degree level, and according to the 2005/36/CE Guideline by the European Parliament and the European Council, from the 7th of September of 2005, is competent for performing the activities related to the production, preservation, and distribution of medicines, as well as to collaborate in the analytical, pharmacotherapeutic, and public health surveillance processes (article 6.2b). To develop these activities is necessary to have a wide knowledge, among others, of the contents and to acquire the competences related to the subject of Chemical Analysis II.
As described in the study program for the degree of Pharmacy, the contents of the subject Chemical Analysis II, within the framework of the Chemistry Module, are mainly based on the study of the main prevailing analytical methods such as optical spectroscopy and non-spectroscopy methods, electrochemical methods, and methods of separation, with a special focus on chromatographic and electrophoretic techniques, which are the most prevalent separation techniques in the pharmaceutical field nowadays. Furthermore, part of the contents of the subject will be focused on other instruments of additional interest, such as mass spectrometry, sensors and automation in pharmaceutical analysis.
RELATION TO OTHER SUBJECTS:
Chemical Analysis II is a subject taken in the first semester of the second course, as the continuation to the subject of Chemical Analysis I, which is taken in the first course of the degree.
Furthermore, to become the pharmacist a competent professional, capable of assuming all the challenges existent in a continuously growing field, which constantly demands new experts, it will be essential to give the students a multidisciplinary education, which has permitted in the past to many pharmacists to give extraordinary contributions in many different fields of knowledge (i.e. botany, chemistry, biochemistry, bromatology, edaphology, parasitology, microbiology, etc.). It is, therefore, clearly exposed the multidisciplinary relation and links among the different basic subjects described in the Degree of Pharmacy.
RELATION TO THE PROFESSION:
Because of this multidisciplinary formation in the scientific, technical, and health science fields, the student who obtained the degree in Pharmacy will be capable to perform the profession of pharmacist, at pharmaceutical companies, in hospital and non-hospital specialized positions, in health analytical laboratories, in the field of health management, and in education or research works.
The subject of Chemical Analysis gives the professional a solid basis of knowledge in classical and instrumental analytical chemistry, in the validation of analytical methods in the pharmaceutical field, as well as in the chemical analysis using separation techniques coupled with different detection techniques (e.g., mass spectrometry) which allow to identify and determine many different compounds of pharmaceutical interest.
Please note that the material created by the teacher and made available to students on the Virtual Campus platform is the property of the teacher. Therefore, taking it out of that context and sharing it with individuals outside of that platform without their consent will be considered a violation of copyright. Furthermore, recording classes and various activities without the explicit consent of the teacher is not allowed.
Engaging in different tests with unauthorized assistance or materials will be considered fraud. In accordance with Article 9 of the Student Evaluation Regulations, any test in which fraud is detected will be deemed invalid and graded as a fail (0), including any detected act of plagiarism. This is without prejudice to any disciplinary proceedings that may be initiated against the student, in accordance with the offenses and penalties specified in the current disciplinary regime.
Course competences | |
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Code | Description |
B01 | Proficiency in a second foreign language at level B1 of the Common European Framework of Reference for Languages. |
B02 | Knowledge of Information and Communication Technologies (ICT). |
B03 | A correct oral and written communication |
B04 | Ethical commitment and professional deontology. |
B05 | Ability to develop those learning skills necessary to undertake further studies. |
EQ01 | Identify, design, prepare, analyse and produce active principles, drugs and other materials and products of sanitary interest. |
EQ02 | Adequately choose the techniques and methodologies for the evaluation, design and application of chemical reagents, laboratory methodologies and analytical techniques. |
EQ03 | Complete standard laboratory processes including the employment of scientific equipment related to synthesis and analysis. |
EQ04 | Evaluate risks/hazards associated to the use of chemical substances and lab processes. |
EQ09 | Know origin, nature, design, production, analysis and drugs quality control and sanitary products. |
EQ10 | Know principles and procedures for the analytical determination of compounds: analytical techniques applied to water, food and environment analysis. |
EQ11 | Know and apply the main structural determination techniques, including spectroscopy. |
G01 | Identify, design, obtain, analyze, control and produce drugs and medicines, as well as other products and raw materials of sanitary interest for human or veterinary use. |
G10 | Design, apply and evaluate clinical reagents, methods and analytical techniques, knowing the basic principles of clinical analysis and the characteristics and contents of laboratory diagnostic reports. |
G11 | Evaluate the toxicological effects of substances and design and apply appropriate tests and trials. |
G12 | Develop hygienic-sanitary analyses, especially those related to food and environment. |
G15 | Recognise own limitations and the need to maintain and update professional competence, with particular emphasis on self-learning of new knowledge based on scientific evidence. |
T01 | Critical thinking skills based on the application of the scientific method |
T02 | Ability to manage quality scientific information, bibliography, specialized databases and resources accessible through the Internet. |
T03 | Handling of basic and specific software for the treatment of information and experimental results. |
T04 | Motivation for quality, safety at work and awareness of environmental issues, with knowledge of the internationally recognised systems for the correct management of these aspects. |
T05 | Organizational, planning and implementation skills. |
T07 | Ability to work as a team and, where appropriate, exercise leadership functions, encouraging entrepreneurship. |
Course learning outcomes | |
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Description | |
Application of the gained knowledge on solution reactions for the qualitative analysis of substances of pharmaceutical interest. | |
To understand the validation strategies of analytical methodologies. | |
To understand the basis of the quality assurance program and of good laboratory practices with application in the pharmaceutical industry, as well as to learn about the control on raw materials, excipients, intermediary and final products. | |
To understand the physicochemical principles in which the different techniques of instrumental analysis are based. | |
Ability to apply the general system of the analytical process to solve simple practical issues with application in different fields. | |
Capacity to estimate the analytical results reliability together with a deep understanding of the statistical criteria applied for their evaluation, especially those related to accuracy and precision. | |
Good environmental practices for the management of chemical substances and residues. | |
Ability to select the ideal instrumental technique for the analytical and structural study of substances of pharmaceutical interest. | |
To identify and to understand the importance of each stage of the analytical process. | |
Capacity to elaborate reports on the analytical results obtained, also understandable for no experts in the field. | |
Self-learning: organization capacity, ability to analyze and to manage the information. | |
To learn the different automatic systems of analysis developed to obtain better productivity in a pharmaceutical lab. | |
Teamwork: critical and self-critical ability. | |
Additional outcomes | |
Description | |
The student will demonstrate its ability at the use of the ICTs | |
The student will correctly use the language for oral and written communication. | |
The student will be capable of undertaking advanced subjects within the Area of Chemistry. |
Training Activity | Methodology | Related Competences (only degrees before RD 822/2021) | ECTS | Hours | As | Com | Description | |
Class Attendance (theory) [ON-SITE] | Combination of methods | B01 B02 B03 B04 B05 EQ01 EQ02 EQ03 EQ04 EQ09 EQ10 EQ11 G01 G10 G11 G12 G15 T01 T02 T03 T04 T05 T07 | 1.44 | 36 | Y | N | The availability of teaching resources will be accessible on the Moodle platform prior to the start of each activity. Additionally, students will have access to supplementary bibliographic and audiovisual material (books, review articles, videos, etc.) in the university library on the Albacete campus. This methodology consists of a combination of methods including EXPOSITORY/LECTURE METHOD and CASE STUDY, which requires active participation from the students through cooperative work, both inside and outside the classroom, as well as the preparation and defense of assignments, problem-solving, and seminars that will be actively resolved throughout the course. This will be considered in the final assessment of the subject. | |
Class Attendance (practical) [ON-SITE] | Practical or hands-on activities | B01 B02 B03 B04 B05 EQ01 EQ02 EQ03 EQ04 EQ09 EQ10 EQ11 G01 G10 G11 G12 G15 T01 T02 T03 T04 T05 T07 | 0.8 | 20 | Y | Y | The practical teaching will be conducted in small groups within the periods established in the academic calendar, which do not overlap with other teaching activities. These practical sessions will take place in laboratories equipped with appropriate resources to achieve the proposed objectives. The student will not be able to pass the course if they do not obtain a PASS grade in the practical module (PASS=grade equal to or higher than 4.0). The laboratory for the Analytical Chemistry II course will involve supervised practical sessions closely related to each of the blocks that make up the theoretical contents of the course. | |
Study and Exam Preparation [OFF-SITE] | Self-study | B01 B02 B03 B04 B05 EQ01 EQ02 EQ03 EQ04 EQ09 EQ10 EQ11 G01 G10 G11 G12 G15 T01 T02 T03 T04 T05 T07 | 3.6 | 90 | Y | N | Individual work that the student will dedicate to studying and learning the subject content. The student may request personal tutorials on specific subject matter by scheduling an appointment in advance with the corresponding professor. | |
Formative Assessment [ON-SITE] | Assessment tests | B01 B02 B03 B04 B05 EQ01 EQ02 EQ03 EQ04 EQ09 EQ10 EQ11 G01 G10 G11 G12 G15 T01 T02 T03 T04 T05 T07 | 0.16 | 4 | Y | N | Specific dates for assessment tests have been scheduled in the academic calendar, which do not overlap with other teaching activities. | |
Total: | 6 | 150 | ||||||
Total credits of in-class work: 2.4 | Total class time hours: 60 | |||||||
Total credits of out of class work: 3.6 | Total hours of out of class work: 90 |
As: Assessable training activity Com: Training activity of compulsory overcoming (It will be essential to overcome both continuous and non-continuous assessment).
Evaluation System | Continuous assessment | Non-continuous evaluation * | Description |
Final test | 70.00% | 70.00% | The student may pass the course through continuous assessment during the semester. To do so, they must take two partial exams that will cover theoretical content as well as problem-solving, seminars, and/or practical cases. 70% of the final grade for the course will be distributed among these two non-compulsory, recoverable partial exams, with each one accounting for 35% of the total course grade. The final grade will be calculated as the average of the two exams ((Exam1 + Exam2) / 2). To pass the course, the student must obtain an overall average grade in the partial exams that allows them to achieve a score of 5.0 or higher, taking into account the remaining grades (laboratory work - 20% - + active participation - 10%). |
Laboratory sessions | 20.00% | 20.00% | Application in the laboratory of the knowledge previously acquired in the theoretical module. The skills acquired in handling chemical substances and laboratory equipment, the attitude of the student, and the proper completion of the laboratory notebook will be evaluated. In addition, a practical exam will be conducted to assess practical content. The overall grade for the practical module will account for 20% of the final grade for the course. Once a PASS grade (equal to or higher than 4.0) is obtained in the practical module, the grade will be retained for the following two academic years, provided that the grade for the practical module is equal to or higher than 5.0. Attendance to the laboratory practical classes is mandatory to pass the module in the regular assessment period. In order to pass the course, the student must have obtained a PASS grade (equal to or higher than 4.0 out of 10) in the practical content module (Block V). If a student does not attend the practical sessions, misses any session without a valid justification, or fails to obtain a PASS grade in the module, they will have to make up for this activity by completing a test (written, oral, or experimental) along with the submission of a practical report that includes the content covered in the practical sessions. The schedule and date for the practical sessions will be provided to the student with sufficient advance notice in order to facilitate course planning. The location where the sessions will take place, the necessary materials, and other relevant details will be provided on the Moodle platform prior to the start of the practical sessions. |
Assessment of active participation | 10.00% | 10.00% | The professor will request the completion of a maximum of two individual assignments (topic development) from the students through the virtual campus and via email (if necessary) during the first three weeks of the first semester. Active participation of the student will be evaluated in both lectures and tutorials, workshops, or other daily in-person activities. Group and individual workshops will be conducted to monitor the student's learning progress, covering theoretical content, seminar solving, and practical cases related to the subject. The student's autonomous work in developing the assigned task(s) throughout the course, as well as oral presentations and/or cooperative work, if applicable, will be positively assessed. Model exercises will be solved on the board (or similar) to help students reinforce the concepts acquired in the theory classes. Active participation of the student in seminars will be evaluated. Students who have not obtained a score in "active participation in class" can improve their grade by submitting one or more activities developed during the course (workshop, written assignment, oral presentation, etc.) as defined by the professor, and this will be described on the virtual campus (Moodle platform) at the beginning of the course. |
Total: | 100.00% | 100.00% |
Not related to the syllabus/contents | |
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Hours | hours |
Class Attendance (theory) [PRESENCIAL][Combination of methods] | 36 |
Class Attendance (practical) [PRESENCIAL][Practical or hands-on activities] | 20 |
Study and Exam Preparation [AUTÓNOMA][Self-study] | 90 |
Formative Assessment [PRESENCIAL][Assessment tests] | 4 |
Global activity | |
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Activities | hours |
Author(s) | Title | Book/Journal | Citv | Publishing house | ISBN | Year | Description | Link | Catálogo biblioteca |
---|---|---|---|---|---|---|---|---|---|
Bard, A. J.; Faulker, L. R | Electrochemical Methods: Fundamentals and Applications | Libro | Chichester | John Wiley and Sons | 0471043720 | 2001 | |||
Gary D. Christian | Química Analítica (6ª Edición) | Libro | Mc Graw Hill | 0-471-21472-8 | 2009 | ||||
L. Hernández y C. González | Introducción al Análisis Instrumental | Libro | Barcelona | Ariel Ciencia | 84-344-8043-8 | 2002 | |||
R. Cela, R.A. Lorenzo, M.C. Casais | Técnicas de separación en Química Analítica | Libro | Madrid | Síntesis | 84-9756-028-0 | 2002 | |||
R. Compañó y A. Ríos | Garantía de la calidad en los laboratorios analíticos | Libro | Madrid | Síntesis | 84-9756-024-8 | 2002 | |||
Rubinson K. A.; Rubinson J.F. | Análisis Instrumental | Libro | Ed. Prentice Hall | 8420529885 | 2004 | ||||
Schwedt, G. | The Essential Guide to Analytical Chemistry | Libro | Chichester | John Wiley and Sons | 0471974123 | 1999 | |||
Skoog D. A., West D. M., Holler F. J. y Crouch S.R. | Fundamentos de Química Analítica | Libro | Thomson Editores | 8497323335 | 2005 | ||||
Skoog, D. A.; Leary, J.J. | Análisis Instrumental | Libro | Madrid | McGraw-Hill | 84-481-0191-X | 1998 | |||
Skoog, D. A; Holler, F. J.; Nieman, T. A | Principios de Análisis Instrumental | Libro | Madrid | McGraw-Hill | 8448127757 | 2010 | |||
Walton, Harold F. | Análisis Químico e Instrumental moderno | Libro | Barcelona | Reverté | 8429175199 | 1983 | |||
Ángel Ríos Castro, María Cruz Bondi Moreno y Bartolomé M. Simonet Suau | Técnicas espectroscópicas en química analítica Volumen I. Aspectos básicos y espectrometría molecular | Libro | Madrid | Síntesis | 2012 | https://www.sintesis.com/biblioteca%20de%20qu%C3%ADmica-138/t%C3%A9cnicas%20espectrosc%C3%B3picas%20en%20qu%C3%ADmica%20anal%C3%ADtica.%20volumen%20i-ebook-1714.html | |||
Ángel Ríos Castro, María Cruz Bondi Moreno y Bartolomé M. Simonet Suau | Técnicas espectroscópicas en química analítica. Volumen II. Espectrometría atómica, de iones y electrones | Madrid | S | 978-84-995893-1-2 | 2012 | https://www.sintesis.com/biblioteca-de-quimica-138/tecnicas-espectroscopicas-en-quimica-analitica-volumen-ii-libro-1715.html |