Although there are no prerequisites for this subject, it is recommended, in order to provide the student with certain guarantees of success, that they have previously taken General Chemistry and Introduction to Laboratory, and have a basic knowledge of Physics and Mathematics.
To achieve this, it is also recommended that students have completed the Physics and Chemistry course in high school and have knowledge in:
Chemical nomenclature and formulation.
Balancing chemical reactions.
Equilibria in solution.
Stoichiometric calculations.
Basic mathematical calculations (solving equations, logarithmic operations, systems of equations...).
Handling of a scientific calculator for performing calculations.
JUSTIFICATION IN THE CURRICULUM:
Pharmacy, as a healthcare profession at the Graduate level, and according to Directive 2005/36/EC of the European Parliament and of the Council, dated September 7, 2005, is responsible for activities related to the production, preservation, and dispensation of medications, as well as collaboration in analytical, pharmacotherapeutic, and public health surveillance processes (Article 6.2b). To carry out these activities, it is necessary to have a broad understanding of the subject matter and acquire the competencies that the Analytical Chemistry I course aims to provide.
As described in the curriculum for the Bachelor's Degree in Pharmacy, the contents of the Analytical Chemistry I course, which falls within the Chemistry module, are mainly based on the study of analytical processes and their stages in the pharmaceutical field, sample collection and preparation, validation of analytical methods, and the development of the necessary knowledge for understanding classical methods of quantitative chemical analysis. Additionally, there is an introduction to analytical separations, although this aspect will be extensively covered in advanced courses, specifically in the Analytical Chemistry II course.
RELATIONSHIP WITH OTHER SUBJECTS OR FIELDS:
The Analytical Chemistry I course is taken in the second semester of the first year, serving as an essential foundation for the continuation of studies with the Analytical Chemistry II course, which is taught in the second year of the degree program.
Furthermore, in order for the Pharmacy graduate to become a competitive professional capable of facing the challenges of a clearly expanding sector that demands new experts, multidisciplinary training is of vital importance. Many pharmacists have contributed to scientific development in diverse fields such as botany, chemistry, biochemistry, bromatology, soil science, parasitology, microbiology, etc. Therefore, the interrelation and multidisciplinary nature of the various fundamental subjects described in the Pharmacy degree program are evident.
RELATIONSHIP WITH THE PROFESSION:
As a result of their multidisciplinary training encompassing scientific, technical, and health sciences areas, Pharmacy graduates are qualified to practice the profession in pharmacies, the pharmaceutical industry, hospital and non-hospital specializations, healthcare analysis laboratories, healthcare management, and educational and research activities. The subject of Analytical Chemistry provides professionals with a solid knowledge base in classical and instrumental analytical chemistry, validation of analytical methods in the pharmaceutical field, as well as chemical analysis using separation techniques coupled with various detection techniques such as mass spectrometry, enabling the identification and confirmation of a wide range of compounds of pharmaceutical interest.
Please note that the materials prepared by the instructor and made available to students on the Virtual Campus platform are the property of the instructor. Taking these materials out of that context and making them available to individuals outside of that platform without the instructor's consent will be considered a violation of copyright. Additionally, it is prohibited to record classes and various activities without the express consent of the instructor.
Engaging in different tests with unauthorized aid or materials will be considered fraud. In accordance with Article 8 of the Student Evaluation Regulations, a test in which fraud is detected will be considered invalid and will be graded as a fail (0), including any detected acts of plagiarism as fraudulent. All of this is without prejudice to the disciplinary procedure that may be initiated against the student, in accordance with the offenses and sanctions stipulated in the current disciplinary regulations.
Course competences | |
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Code | Description |
B01 | Proficiency in a second foreign language at level B1 of the Common European Framework of Reference for Languages. |
B02 | Knowledge of Information and Communication Technologies (ICT). |
B03 | A correct oral and written communication |
B04 | Ethical commitment and professional deontology. |
B05 | Ability to develop those learning skills necessary to undertake further studies. |
EQ01 | Identify, design, prepare, analyse and produce active principles, drugs and other materials and products of sanitary interest. |
EQ02 | Adequately choose the techniques and methodologies for the evaluation, design and application of chemical reagents, laboratory methodologies and analytical techniques. |
EQ03 | Complete standard laboratory processes including the employment of scientific equipment related to synthesis and analysis. |
EQ04 | Evaluate risks/hazards associated to the use of chemical substances and lab processes. |
EQ06 | Know and understand the characteristics of chemical reactions in solution, the different states of matter and the principles of thermodynamics and their application to pharmaceutical sciences. |
EQ09 | Know origin, nature, design, production, analysis and drugs quality control and sanitary products. |
EQ10 | Know principles and procedures for the analytical determination of compounds: analytical techniques applied to water, food and environment analysis. |
EQ11 | Know and apply the main structural determination techniques, including spectroscopy. |
G01 | Identify, design, obtain, analyze, control and produce drugs and medicines, as well as other products and raw materials of sanitary interest for human or veterinary use. |
G02 | Evaluate the therapeutic and toxic effects of substances with pharmacological activity. |
G03 | Know how to apply the scientific method and acquire skills in the handling of legislation, sources of information, bibliography, elaboration of protocols and other aspects considered necessary for the design and critical evaluation of preclinical and clinical trials. |
G04 | Design, prepare, supply and dispense medicines and other products of health interest. |
G05 | Provide therapeutic advice in pharmacotherapy and dietotherapy, as well as in the nutritional and food field in the establishments where they provide services. |
G06 | Promote the rational use of medicines and medical devices, as well as to acquire basic knowledge in clinical management, health economics and the efficient use of health resources. |
G07 | Identify, evaluate and assess problems related to drugs and medicines, as well as participate in pharmacovigilance activities. |
G08 | Conducting clinical and social pharmacy activities, following the pharmaceutical care cycle. |
G09 | Intervene in health promotion and disease prevention activities at the individual, family and community levels, with an integral and multi-professional vision of the health-disease process. |
G10 | Design, apply and evaluate clinical reagents, methods and analytical techniques, knowing the basic principles of clinical analysis and the characteristics and contents of laboratory diagnostic reports. |
G11 | Evaluate the toxicological effects of substances and design and apply appropriate tests and trials. |
G12 | Develop hygienic-sanitary analyses, especially those related to food and environment. |
G13 | Develop communication and information skills, both oral and written, to deal with patients and users of the centre where they carry out their professional activity. Promote the capacity to work and collaborate with multidisciplinary teams and those related to other health professionals. |
G14 | Know the ethical and deontological principles according to the legislative, regulatory and administrative provisions governing professional practice, understanding the ethical implications of health in a changing social context. |
G15 | Recognise own limitations and the need to maintain and update professional competence, with particular emphasis on self-learning of new knowledge based on scientific evidence. |
T01 | Critical thinking skills based on the application of the scientific method |
T02 | Ability to manage quality scientific information, bibliography, specialized databases and resources accessible through the Internet. |
T03 | Handling of basic and specific software for the treatment of information and experimental results. |
T04 | Motivation for quality, safety at work and awareness of environmental issues, with knowledge of the internationally recognised systems for the correct management of these aspects. |
T05 | Organizational, planning and implementation skills. |
T06 | Ability to address human resources decision-making and management. |
T07 | Ability to work as a team and, where appropriate, exercise leadership functions, encouraging entrepreneurship. |
T08 | Develop interpersonal skills and the ability to function in an international and multicultural context. |
Course learning outcomes | |
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Description | |
Application of the gained knowledge on solution reactions for the qualitative analysis of substances of pharmaceutical interest. | |
To understand the validation strategies of analytical methodologies. | |
To understand the basis of the quality assurance program and of good laboratory practices with application in the pharmaceutical industry, as well as to learn about the control on raw materials, excipients, intermediary and final products. | |
To understand the physicochemical principles in which the different techniques of instrumental analysis are based. | |
Ability to apply the general system of the analytical process to solve simple practical issues with application in different fields. | |
Capacity to estimate the analytical results reliability together with a deep understanding of the statistical criteria applied for their evaluation, especially those related to accuracy and precision. | |
Good environmental practices for the management of chemical substances and residues. | |
Ability to select the ideal instrumental technique for the analytical and structural study of substances of pharmaceutical interest. | |
To identify and to understand the importance of each stage of the analytical process. | |
Capacity to elaborate reports on the analytical results obtained, also understandable for no experts in the field. | |
Self-learning: organization capacity, ability to analyze and to manage the information. | |
To learn the different automatic systems of analysis developed to obtain better productivity in a pharmaceutical lab. | |
To differentiate the sense of chemical reactions, their extension and influence on concurrent equilibria. To interpret titration curves. | |
Teamwork: critical and self-critical ability. | |
Additional outcomes | |
Description | |
To learn the correct use of the language for an adequate oral and written communication. | |
The student will be capable of undertaking advanced subjects within the area of Chemistry. | |
Acquisition of the capacity to assimilate new principles and knowledge, as well as critical reasoning based on the evidences and the scientific method. | |
To apply the acquired knowledge on the fundamental principles of classical analytical methods and techniques to the drugs and pharmaceutical analysis, as well as for the analysis of potentially toxic substances or of health interest. |
Training Activity | Methodology | Related Competences (only degrees before RD 822/2021) | ECTS | Hours | As | Com | Description | |
Class Attendance (theory) [ON-SITE] | Lectures | B01 B02 B03 B04 B05 EQ01 EQ02 EQ03 EQ04 EQ06 EQ09 EQ10 EQ11 G01 G02 G03 G04 G05 G06 G07 G08 G09 G10 G11 G12 G13 G14 G15 T01 T02 T03 T04 T05 T06 | 1.44 | 36 | Y | N | The availability of teaching resources will be accessible on the Moodle platform before the start of each activity. In addition, students will have access to complementary bibliographic and audiovisual materials (books, review articles, videos, etc.) at the university library on the Albacete campus. The active participation of students through cooperative work, both in and outside the classroom, as well as in the preparation and defense of assignments, case studies, problem-solving, workshops, and seminars, which will be actively resolved throughout the course, will be taken into account in the final assessment of the subject. | |
Laboratory practice or sessions [ON-SITE] | Practical or hands-on activities | B01 B02 B03 B04 B05 EQ01 EQ02 EQ03 EQ04 EQ06 EQ09 EQ10 EQ11 G01 G02 G03 G04 G05 G06 G07 G08 G09 G10 G11 G12 G13 G14 G15 T01 T02 T03 T04 T05 T06 | 0.8 | 20 | Y | Y | Practical teaching will be conducted in small groups within the periods established in the academic calendar, which do not overlap with other instructional activities. They will take place in laboratories equipped with the necessary resources to achieve the proposed objectives. The student will not be able to pass the subject unless they obtain a PASS grade in the practical module (PASS = grade equal to or greater than 4.0). The laboratory component of the Analytical Chemistry I course will consist of supervised practices closely related to the theoretical contents of the subject. | |
Study and Exam Preparation [OFF-SITE] | Self-study | B01 B02 B03 B04 B05 EQ01 EQ02 EQ03 EQ04 EQ06 EQ09 EQ10 EQ11 G01 G02 G03 G04 G05 G06 G07 G08 G09 G10 G11 G12 G13 G14 G15 T01 T02 T03 T04 T05 T06 T07 T08 | 3.6 | 90 | N | N | Individual work that the student will dedicate to studying and learning the contents of the subject. The student can request personal tutoring on the subject matter by scheduling an appointment in advance with the corresponding professor. | |
Formative Assessment [ON-SITE] | Assessment tests | B01 B02 B03 B04 B05 EQ01 EQ02 EQ03 EQ04 EQ06 EQ09 EQ10 EQ11 G01 G02 G03 G04 G05 G06 G07 G08 G09 G10 G11 G12 G13 G14 G15 T01 T02 T03 T04 T05 T06 T07 T08 | 0.16 | 4 | Y | Y | Specific dates have been reserved in the academic calendar for evaluation tests that do not overlap with other instructional activities. | |
Total: | 6 | 150 | ||||||
Total credits of in-class work: 2.4 | Total class time hours: 60 | |||||||
Total credits of out of class work: 3.6 | Total hours of out of class work: 90 |
As: Assessable training activity Com: Training activity of compulsory overcoming (It will be essential to overcome both continuous and non-continuous assessment).
Evaluation System | Continuous assessment | Non-continuous evaluation * | Description |
Laboratory sessions | 20.00% | 20.00% | Application in the laboratory of the knowledge previously acquired in the theoretical module. The skill acquired in handling chemical substances, as well as laboratory equipment, the student's attitude, and the proper preparation of the laboratory notebook, will be evaluated. Additionally, a practical exam will be conducted. The overall grade for the practical module will account for 20% of the final grade for the subject. Once a PASS grade (equal to or greater than 4.0) is obtained in the practical module, the grade will be valid for the following two academic years, as long as the practical module grade is equal to or higher than 5.0. Attendance to laboratory practical classes is mandatory to pass the module in the regular exam session. To pass the subject, the student must have obtained a PASS grade (equal to or higher than 4.0 out of 10) in the Practical Content Module. In case of non-attendance to practical sessions, absence from any session without proper justification, or failure to achieve a PASS grade in the module, the student will have to make up for this activity by completing a test (written, oral, or experimental) along with the submission of a lab report that includes the content of the missed sessions. The location where practical sessions will take place and the necessary materials, among other details, will be provided on the Moodle platform prior to the start of the practical lessons. |
Assessment of active participation | 10.00% | 10.00% | The professor will request students, through the virtual campus or via email (if necessary), during the first three weeks of the second semester, to complete a maximum of two individual theoretical assignments (topic development and/or practical cases). The active participation of students will also be evaluated, both in lectures and in tutorials and daily activities. Group and individual tutorials will be conducted to monitor the students' learning progress, covering theoretical content and the resolution of seminars and/or problems related to the subject. The students' autonomous work in developing the assigned task(s) throughout the course will be positively valued, as well as oral presentations and/or cooperative work, if applicable. Model exercises will be solved on the board to help students understand the concepts acquired in the theory classes. The active participation of students in seminars will be evaluated. Students who have not received a score for "participation with achievement in class" will have the opportunity to improve their grade by presenting one or several activities developed during the course (workshop, written assignment, oral presentation, etc.), as defined by the professor and described on the virtual campus during the first three weeks of the second semester. |
Final test | 70.00% | 70.00% | The student can pass the subject through continuous assessment during the course. To do so, they must take two final exams that will include theoretical concepts as well as problem-solving, seminars, or practical cases. 70% of the final grade for the subject will be distributed in these two mandatory recoverable final exams, with each exam accounting for 35% of the total subject grade. The final grade will be calculated as the average ((Exam1 + Exam2)/2) of the two exams. To pass the subject, the student must achieve a sufficient average grade in the final exams, resulting in a score of 5.0 or higher after considering the remaining grades (laboratory practices - 20% - + participation with achievement - 10% -). |
Total: | 100.00% | 100.00% |
Not related to the syllabus/contents | |
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Hours | hours |
Class Attendance (theory) [PRESENCIAL][Lectures] | 36 |
Laboratory practice or sessions [PRESENCIAL][Practical or hands-on activities] | 20 |
Study and Exam Preparation [AUTÓNOMA][Self-study] | 90 |
Formative Assessment [PRESENCIAL][Assessment tests] | 4 |
Global activity | |
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Activities | hours |