Guías Docentes Electrónicas
Castellano
Exportar en PDF
Castellano Inglés
1. General information
Course:
ADVANCED TECHNIQUES OF INSTRUMENTAL ANALYSIS
Code:
310586
Type:
CORE COURSE
ECTS credits:
6
Degree:
2366 - MASTER DEGREE PROGRAMME IN CHEMICAL
Academic year:
2023-24
Center:
1 - FACULTY OF SCIENCE AND CHEMICAL TECHNOLOGY
Group(s):
20 
Year:
1
Duration:
First semester
Main language:
Spanish
Second language:
English
Use of additional languages:
English Friendly:
Y
Web site:
Bilingual:
N
Lecturer: ALFONSO ARANDA RUBIO - Group(s): 20 
Building/Office
Department
Phone number
Email
Office hours
Marie Curie/2ª planta
QUÍMICA FÍSICA
926051915
alfonso.aranda@uclm.es
Tuesday, Wednesday and Thursday from 16:00 to 18:00

Lecturer: BERNABE BALLESTEROS RUIZ - Group(s): 20 
Building/Office
Department
Phone number
Email
Office hours
Marie Curie, primera planta
QUÍMICA FÍSICA
926052049
bernabe.ballesteros@uclm.es
L,M: 9-11h J: 17-19h

Lecturer: JOSE ANTONIO MURILLO PULGARIN - Group(s): 20 
Building/Office
Department
Phone number
Email
Office hours
Edificio San Alberto Magno
Q. ANALÍTICA Y TGIA. ALIMENTOS
3441
joseantonio.murillo@uclm.es
Tues., W., Thu. 17:00 to 19:00h.

2. Pre-Requisites
Not established
3. Justification in the curriculum, relation to other subjects and to the profession

Technological advances in fields such as mass spectrometry and laser technology are enabling the development of new scientific tools.

Knowledge of the principles, equipment and applications enables the use of advanced instrumental techniques in the field of chemistry research.


4. Degree competences achieved in this course
Course competences
Code Description
CB07 Students are able to apply their acquired knowledge and problem-solving skills in new or unfamiliar environments within broader (or multidisciplinary) contexts related to their field of study.
CB10 Students possess the learning skills that will enable them to continue studying in a largely self-directed or autonomous way.
CE04 Evaluate the usefulness of separation, analysis and structural determination techniques for joint application in problem solving, and be skilled in the use of such techniques in both research and routine laboratories applying methods of organic and inorganic analysis and/or synthesis.
CE06 Assess the principles of sustainable chemistry and safety standards for the handling of known or newly synthesised chemicals.
CE07 To learn about the possibilities offered by new analytical methodologies in different fields of application, as well as the current trends in analytical chemistry of interest for the development of R+D+I or its implementation in specialised control laboratories.
CG01 Transfer the concepts and fundamentals of chemistry in the context of scientific research and/or in the specialised profession of the chemist.
CG02 To achieve advanced training in the fundamentals and potential of the instrumental techniques available in chemistry for the development of scientific research and/or application in specialised control laboratories.
5. Objectives or Learning Outcomes
Course learning outcomes
Description
Acquire knowledge of the different ionisation sources, mass analysers and interfaces used in mass spectrometry.  To know the different couplings of mass spectrometry with different separation techniques and their applications.
To understand the fundamentals and applications of laser technology and laser-induced fluorescence.
Acquire scientific criteria for the selection of the most appropriate separation technique according to the requirements of the components and samples to be analysed, as well as the quality of the required results.
Acquire a critical spirit to modify and improve analytical procedures already established in the literature.
To learn about the possibilities offered by new luminescent methodologies in different fields of application such as environmental analysis, pharmacology, food safety.
To know how to select the most appropriate luminescent or voltammetric technique for the resolution of an analytical problem depending on the nature of the analyte and the complexity of the matrix, without loss of sensitivity and selectivity.
Additional outcomes
Not established.
6. Units / Contents
  • Unit 1: Mass spectrometry. Ionisation techniques and ion discrimination.
    • Unit 1.1: History, evolution and fundamentals of mass spectrometry. Concepts. Mass spectra. Isotopic effects.
    • Unit 1.2: Vacuum technology. Vacuum and high vacuum pumping systems and instrumentation.
    • Unit 1.3: Ionisation methods: Volatile and low volatile substances. Electronic ionisation, chemical ionisation, field ionisation, laser desorption, fast atom bombardment, secondary ions, electrospray. Ionisation sources at atmospheric pressure.
    • Unit 1.4: Mass analysers. Ion separation. Sectors, quadrupole, Ion Trap, cyclotron, time of flight. Tandem mass spectrometry.
    • Unit 1.5: Ion detectors. SEM, Channeltron, scintillation and multichannel.
    • Unit 1.6: Operating modes: Scan, SIM, SRM, MRM and use of spectrum libraries.
  • Unit 2: Instrumental hybridisation with mass spectrometric detection.
    • Unit 2.1: Couplings and different sample handling and insertion systems.
    • Unit 2.2: Combined use with other techniques: GC-MS, LC-MS, ICP-MS, PTR-MS, Aerosol Mass Spectrometry. Sampling with SPME.
  • Unit 3: Laser-induced fluorescence. Fundamentals and instrumentation.
    • Unit 3.1: Characteristics of laser radiation. Types of lasers.
    • Unit 3.2: Laser spectroscopy
    • Unit 3.3: Kinetic and spectroscopic applications of gas-phase LIF.
  • Unit 4: Analytical applications of hybridisations with mass spectrometric detection. Analytical applications of laser-induced fluorescence techniques.
    • Unit 4.1: Mass spectrometric detection with hybridisations.
    • Unit 4.2: Applications of laser-induced fluorescence to the characterisation of compounds. Quantitative applications. Kinetic spectroscopic applications. Other applications.
  • Unit 5: Scattering techniques. Optical rotating scattering and diffuse reflectance.
    • Unit 5.1: Non-spectroscopic optical techniques. General characteristics.
    • Unit 5.2: Optical scattering. Optical rotating scattering and diffuse reflectance.
  • Unit 6: Electrochemical characterisation techniques by cyclic voltammetry.
    • Unit 6.1: Basics of voltamperometry.
    • Unit 6.2: Cyclic voltammetry. Comparison with linear scanning voltamperometry. Characterisation by cyclic voltamperometry
    • Unit 6.3: Example of applications.
7. Activities, Units/Modules and Methodology
Training Activity Methodology Related Competences (only degrees before RD 822/2021) ECTS Hours As Com Description
Writing of reports or projects [OFF-SITE] Self-study CB07 CB10 1.52 38 N N
Class Attendance (theory) [ON-SITE] Lectures CE04 CE06 CE07 1.12 28 N N
Study and Exam Preparation [OFF-SITE] Self-study CG01 CG02 1.48 37 N N
Analysis of articles and reviews [OFF-SITE] Self-study CB10 CE04 CE06 CE07 1.28 32 N N
Project or Topic Presentations [ON-SITE] Case Studies CB07 CG01 0.08 2 Y Y
Other off-site activity [OFF-SITE] Combination of methods CB10 CE07 0.16 4 Y Y
Progress test [ON-SITE] Assessment tests CE04 CE06 CE07 0.08 2 Y Y
Workshops or seminars [ON-SITE] Problem solving and exercises CB07 CE04 CE06 CE07 CG01 0.2 5 Y Y
Group tutoring sessions [ON-SITE] Cooperative / Collaborative Learning CB07 CG01 0.08 2 N N
Total: 6 150
Total credits of in-class work: 1.56 Total class time hours: 39
Total credits of out of class work: 4.44 Total hours of out of class work: 111

As: Assessable training activity
Com: Training activity of compulsory overcoming (It will be essential to overcome both continuous and non-continuous assessment).

8. Evaluation criteria and Grading System
Evaluation System Continuous assessment Non-continuous evaluation * Description
Final test 40.00% 100.00% Exam with theoretical and practical contents
Assessment of problem solving and/or case studies 40.00% 0.00% Reports or work developed during the course
Other methods of assessment 20.00% 0.00% On line activities
Total: 100.00% 100.00%  
According to art. 4 of the UCLM Student Evaluation Regulations, it must be provided to students who cannot regularly attend face-to-face training activities the passing of the subject, having the right (art. 12.2) to be globally graded, in 2 annual calls per subject , an ordinary and an extraordinary one (evaluating 100% of the competences).

Evaluation criteria for the final exam:
  • Continuous assessment:
    Assessment of works or reports: 40%.
    Final exam: 40%
    Assessment of online activities 20%.
  • Non-continuous evaluation:
    For students who justify at the beginning of the course that they cannot follow the continuous assessment, a final test will be held with theoretical and practical questions on the subject of the course: 100%.

Specifications for the resit/retake exam:
In the case of continuous assessment, the grades obtained during the course will be taken into account:
Assessment of reports or assignments: 40%.
Final test: 40%.
Assessment of online activities: 20%.
Only the assessment blocks not passed during the course must be passed.
Specifications for the second resit / retake exam:
Final test with theoretical and practical questions on the subject matter of the course: 100%
9. Assignments, course calendar and important dates
Not related to the syllabus/contents
Hours hours

Unit 1 (de 6): Mass spectrometry. Ionisation techniques and ion discrimination.
Activities Hours
Writing of reports or projects [AUTÓNOMA][Self-study] 9
Class Attendance (theory) [PRESENCIAL][Lectures] 7
Study and Exam Preparation [AUTÓNOMA][Self-study] 8
Analysis of articles and reviews [AUTÓNOMA][Self-study] 8
Project or Topic Presentations [PRESENCIAL][Case Studies] .5
Other off-site activity [AUTÓNOMA][Combination of methods] 1
Workshops or seminars [PRESENCIAL][Problem solving and exercises] 1
Group tutoring sessions [PRESENCIAL][Cooperative / Collaborative Learning] .5

Unit 2 (de 6): Instrumental hybridisation with mass spectrometric detection.
Activities Hours
Writing of reports or projects [AUTÓNOMA][Self-study] 4
Class Attendance (theory) [PRESENCIAL][Lectures] 2
Study and Exam Preparation [AUTÓNOMA][Self-study] 4
Analysis of articles and reviews [AUTÓNOMA][Self-study] 3
Workshops or seminars [PRESENCIAL][Problem solving and exercises] 1

Unit 3 (de 6): Laser-induced fluorescence. Fundamentals and instrumentation.
Activities Hours
Writing of reports or projects [AUTÓNOMA][Self-study] 6
Class Attendance (theory) [PRESENCIAL][Lectures] 5
Study and Exam Preparation [AUTÓNOMA][Self-study] 6
Analysis of articles and reviews [AUTÓNOMA][Self-study] 5
Project or Topic Presentations [PRESENCIAL][Case Studies] .5
Other off-site activity [AUTÓNOMA][Combination of methods] 1
Progress test [PRESENCIAL][Assessment tests] 1
Workshops or seminars [PRESENCIAL][Problem solving and exercises] 1
Group tutoring sessions [PRESENCIAL][Cooperative / Collaborative Learning] .5

Unit 4 (de 6): Analytical applications of hybridisations with mass spectrometric detection. Analytical applications of laser-induced fluorescence techniques.
Activities Hours
Writing of reports or projects [AUTÓNOMA][Self-study] 6
Class Attendance (theory) [PRESENCIAL][Lectures] 4
Study and Exam Preparation [AUTÓNOMA][Self-study] 6
Analysis of articles and reviews [AUTÓNOMA][Self-study] 5

Unit 5 (de 6): Scattering techniques. Optical rotating scattering and diffuse reflectance.
Activities Hours
Writing of reports or projects [AUTÓNOMA][Self-study] 6
Class Attendance (theory) [PRESENCIAL][Lectures] 5
Study and Exam Preparation [AUTÓNOMA][Self-study] 6
Analysis of articles and reviews [AUTÓNOMA][Self-study] 5
Other off-site activity [AUTÓNOMA][Combination of methods] 1
Workshops or seminars [PRESENCIAL][Problem solving and exercises] 1

Unit 6 (de 6): Electrochemical characterisation techniques by cyclic voltammetry.
Activities Hours
Writing of reports or projects [AUTÓNOMA][Self-study] 7
Class Attendance (theory) [PRESENCIAL][Lectures] 5
Study and Exam Preparation [AUTÓNOMA][Self-study] 7
Analysis of articles and reviews [AUTÓNOMA][Self-study] 6
Project or Topic Presentations [PRESENCIAL][Case Studies] 1
Other off-site activity [AUTÓNOMA][Combination of methods] 1
Progress test [PRESENCIAL][Assessment tests] 1
Workshops or seminars [PRESENCIAL][Problem solving and exercises] 1
Group tutoring sessions [PRESENCIAL][Cooperative / Collaborative Learning] 1

Global activity
Activities hours
10. Bibliography and Sources
Author(s) Title Book/Journal Citv Publishing house ISBN Year Description Link Catálogo biblioteca
 
 
-Edmond de Hoffmann y Vicent Stroobant Mass Spectrometry. Principles and Applications Libro Wiley 2007  
-Gross, J. Mass Spectrometry: a textbook Libro Springer 2011  
-Helmut H. Telle, Angel González Ureña, Robert J. Donovan Laser Chemistry Libro Wiley 2007  
-Orazio Svelto, Principles of Lasers Libro Springer 2009  
Eric Plum, V. A. Fedotov and Nikolay I. Zheludev Specular optical activity of achiral metasurfaces Revista. Applied Physics Letters, 108(14) 2015  
Laane, Jaan Frontiers and Advances in Molecular Spectroscopy Libro Elsevier 2017  
Requena Rodríguez, A. Espectroscopía volume II: Métodos Avanzados. Libro García Moroto ediciones 2020  
Watson, J; Sparkman, D. Introduction to Mass Spectrometry, Libro Wiley 2007  



Web mantenido y actualizado por el Servicio de informática