1. General information
Course:
PHARMACOLOGY AND PHARMACOTHERAPY I
Code:
14329
Type:
CORE COURSE
ECTS credits:
6
Degree:
376 - UNDERGRADUATE DEGREE PROGRAMME IN PHARMACY
Academic year:
2023-24
Center:
14 - FACULTY OF PHARMACY
Group(s):
10
Year:
4
Duration:
First semester
Main language:
Spanish
Second language:
English
Use of additional languages:
English Friendly:
Y
Web site:
Bilingual:
N
Lecturer:
VALENTIN CEÑA CALLEJO
- Group(s):
10
Building/Office
Department
Phone number
Email
Office hours
Facultad de Medicina
CIENCIAS MÉDICAS
2951
valentin.cena@uclm.es
Lecturer:
INMACULADA CONCEPCION POSADAS MAYO
- Group(s):
10
Building/Office
Department
Phone number
Email
Office hours
Facultad de Farmacia
CIENCIAS MÉDICAS
2953
inmaculada.posadas@uclm.es
2. Pre-Requisites
Students must bear in mind that in order to pass this subject they must have previously studied and passed Human Anatomy, Biology and Organic Chemistry I in the first year; Organic Chemistry II, Physical Chemistry I and II, Biochemistry I and II, Immunology and Physiology in the second year, General Pharmacology, Physiopathology and Biopharmacology and Pharmacokinetics in the third year.
3. Justification in the curriculum, relation to other subjects and to the profession
PHARMACOLOGY AND PHARMACOTHERAPY I is one of the subjects that make up Module 5 of the UCLM Degree in Pharmacy Syllabus to be taught during the FIRST four-month period of the 4th year. It is therefore aimed at second cycle students who have already had contact with Basic Sciences in the first cycle. Therefore, students should have already passed the recommended prior knowledge to adequately undertake this subject, knowledge that is achieved in other subjects such as Biology, Human Anatomy, Organic Chemistry, Physical chemistry, Physiology, Biochemistry and Molecular Biology, Immunology, Bio-pharmacy and Pharmacokinetics and General Pharmacology. The notions of these other subjects facilitate the learning process and the acquisition of new knowledge about the properties and mechanism of action of drugs to lay the foundations for rational and effective drug therapy.
Based on the approaches and objectives of the program detailed below, this subject incorporates a wealth of knowledge and in turn provides essential foundations about medicines, on which the correct and rational use of medicines is articulated and supported. A thorough knowledge of the physical, chemical, and biological interactions on the results of therapy makes pharmacists unique among health professionals in understanding the entity of medicines, the release characteristics of formulations, the distribution of active ingredients in different compartments, and the physiological and pharmacological results of their interactions with the biological organism.
The pharmacist is a drug professional who must possess the ability to find, integrate and apply information from pharmaceutical sciences to solve pharmacotherapeutic problems, which will enable him/her to:
- To inform and advise patients on medication as part of their pharmaceutical care work.
- To participate in and develop teaching tasks aimed at training students of the Degree in Pharmacy and other health professionals.
- To participate in research aimed at the development of new drugs and the identification of possible therapeutic targets.
4. Degree competences achieved in this course
| Course competences | |
|---|---|
| Code | Description |
| B01 | Proficiency in a second foreign language at level B1 of the Common European Framework of Reference for Languages. |
| B02 | Knowledge of Information and Communication Technologies (ICT). |
| B03 | A correct oral and written communication |
| B04 | Ethical commitment and professional deontology. |
| B05 | Ability to develop those learning skills necessary to undertake further studies. |
| EM01 | Using drugs safely, taking into account their physical properties and the kind of vehicles directly related with their use. |
| EM04 | Study the effects of substances with pharmacological activity. |
| EM05 | Know and understand the techniques used in the design and evaluation of pre-clinical and clinical trials. |
| EM07 | Promote the rational use of medicines and health products. |
| EM08 | Acquire the necessary skills to provide therapeutic advices in pharmacology and dietetics, as well as to give nutritional advice to the users of the establishment where they provide customer service |
| EM12 | Acquire a detailed knowledge about the drugs properties and their mechanism of action |
| EM22 | Interaction of drugs with other drugs or substances. Prevention and treatment. |
| G01 | Identify, design, obtain, analyze, control and produce drugs and medicines, as well as other products and raw materials of sanitary interest for human or veterinary use. |
| G02 | Evaluate the therapeutic and toxic effects of substances with pharmacological activity. |
| G03 | Know how to apply the scientific method and acquire skills in the handling of legislation, sources of information, bibliography, elaboration of protocols and other aspects considered necessary for the design and critical evaluation of preclinical and clinical trials. |
| G04 | Design, prepare, supply and dispense medicines and other products of health interest. |
| G05 | Provide therapeutic advice in pharmacotherapy and dietotherapy, as well as in the nutritional and food field in the establishments where they provide services. |
| G06 | Promote the rational use of medicines and medical devices, as well as to acquire basic knowledge in clinical management, health economics and the efficient use of health resources. |
| G07 | Identify, evaluate and assess problems related to drugs and medicines, as well as participate in pharmacovigilance activities. |
| G08 | Conducting clinical and social pharmacy activities, following the pharmaceutical care cycle. |
| G09 | Intervene in health promotion and disease prevention activities at the individual, family and community levels, with an integral and multi-professional vision of the health-disease process. |
| G10 | Design, apply and evaluate clinical reagents, methods and analytical techniques, knowing the basic principles of clinical analysis and the characteristics and contents of laboratory diagnostic reports. |
| G11 | Evaluate the toxicological effects of substances and design and apply appropriate tests and trials. |
| G12 | Develop hygienic-sanitary analyses, especially those related to food and environment. |
| G13 | Develop communication and information skills, both oral and written, to deal with patients and users of the centre where they carry out their professional activity. Promote the capacity to work and collaborate with multidisciplinary teams and those related to other health professionals. |
| G14 | Know the ethical and deontological principles according to the legislative, regulatory and administrative provisions governing professional practice, understanding the ethical implications of health in a changing social context. |
| G15 | Recognise own limitations and the need to maintain and update professional competence, with particular emphasis on self-learning of new knowledge based on scientific evidence. |
| T01 | Critical thinking skills based on the application of the scientific method |
| T02 | Ability to manage quality scientific information, bibliography, specialized databases and resources accessible through the Internet. |
| T03 | Handling of basic and specific software for the treatment of information and experimental results. |
| T04 | Motivation for quality, safety at work and awareness of environmental issues, with knowledge of the internationally recognised systems for the correct management of these aspects. |
| T05 | Organizational, planning and implementation skills. |
| T06 | Ability to address human resources decision-making and management. |
| T07 | Ability to work as a team and, where appropriate, exercise leadership functions, encouraging entrepreneurship. |
| T08 | Develop interpersonal skills and the ability to function in an international and multicultural context. |
5. Objectives or Learning Outcomes
| Course learning outcomes | |
|---|---|
| Description | |
| Acquire a detailed knowledge for the use of drugs database useful to the search for information on drugs and related topics. | |
| Learning basic pharmacological terminology, and acquire a detailed knowledge about pharmacological targets and pharmacokinetics processes suffered by drugs in the body. | |
| To know the behaviour of the drugs in the body in a specific way for each of the therapeutic groups. | |
| Identify and evaluate the different types of adverse reactions associated with the pharmacological treatments. | |
| Solving and interpretation of experimental data. Learning the right handling of the experimental animal. | |
| Identify the most common types of pharmacological interactions. Learning to visualize and detect new potential interactions. | |
| Identifying the different effects derived from the pharmacological action, differentiating the main effects and the side effects, leading the projection towards the understanding and rationalization of therapeutics. | |
| Promote the rational use of drugs. | |
| Additional outcomes | |
| Not established. |
6. Units / Contents
-
Unit 1: Pharmacology of the Autonomic Nervous System
-
Unit 2: Autacoids
-
Unit 3: Pharmacology of the inflammatory response
-
Unit 4: Pharmacology of the respiratory system
-
Unit 5: Pharmacology of the cardiovascular system
-
Unit 6: Pahrmacology of the Central Nervous System
-
Unit 7: Laboratory
ADDITIONAL COMMENTS, REMARKS
The unit content will be specify in Moodle
7. Activities, Units/Modules and Methodology
| Training Activity | Methodology | Related Competences (only degrees before RD 822/2021) | ECTS | Hours | As | Com | Description | |
| Class Attendance (theory) [ON-SITE] | Combination of methods | B01 B02 B03 B04 B05 EM12 EM22 G01 G02 G03 G04 G05 G06 G07 G08 G09 G10 G11 G12 G13 G14 G15 T01 T02 T03 T04 T05 T06 T07 T08 | 1.38 | 34.5 | Y | N | The teaching resources will be accessible on the Moodle platform before the start of the activities. In addition, students will have access to complementary bibliographic material (books, review articles) in the university library of the Albacete campus. The teaching methodology through the combination of methods will contemplate the expository method/lecture. The active participation of the student, through cooperative work both in and out of the classroom and in the preparation and defence of workshops, and in the resolution of questions or cases proposed by the teacher throughout the course, or any other activity proposed by the teacher, will be taken into account in the final assessment of the course. | |
| Class Attendance (practical) [ON-SITE] | Practical or hands-on activities | B01 B02 B03 B04 B05 EM01 EM04 EM05 EM07 EM08 G01 G02 G03 G04 G05 G06 G07 G08 G09 G10 G11 G12 G13 G14 G15 | 0.8 | 20 | Y | Y | Practical teaching will be given in small groups within the periods established in the academic calendar and will not coincide with other teaching activities. They will be carried out in laboratories equipped with the appropriate means to achieve the proposed objectives. These activities are MANDATORY and students will not be able to pass the course if they are not carried out properly. | |
| Study and Exam Preparation [OFF-SITE] | Self-study | B01 B02 B03 B04 B05 EM01 EM04 EM05 EM07 EM08 G01 G02 G03 G04 G05 G06 G07 G08 G09 G10 G11 G12 G13 G14 G15 T01 T02 T03 T04 T05 T06 T07 T08 | 3.28 | 82 | Y | N | Students may request personal tutorials on the contents of the course by previously requesting an interview with the teacher. | |
| Formative Assessment [ON-SITE] | Assessment tests | B01 B02 B03 B04 B05 EM01 EM04 EM05 EM07 EM08 G01 G02 G03 G04 G05 G06 G07 G08 G09 G10 G11 G12 G13 G14 G15 T01 T02 T03 T04 T05 T06 T07 T08 | 0.16 | 4 | Y | Y | Specific dates have been set aside in the academic calendar so that the assessment tests do not coincide with other teaching activities. | |
| Group tutoring sessions [ON-SITE] | Group tutoring sessions | B03 B04 B05 T01 T02 T03 | 0.06 | 1.5 | Y | N | Group tutorials will be held in which different aspects proposed by both the teacher and the students will be addressed. | |
| On-line debates and forums [OFF-SITE] | Problem solving and exercises | EM01 EM04 EM05 EM07 EM08 EM12 EM22 G02 G03 G06 G07 T01 T02 T03 | 0.32 | 8 | Y | N | This is a Virtual Learning activity, in which the teacher will provide students in the virtual space Moodle, various questionnaires and problems that will help students to determine their level of knowledge of the subject. students must study the proposed cases, and proceed to their resolution. | |
| Total: | 6 | 150 | ||||||
| Total credits of in-class work: 2.4 | Total class time hours: 60 | |||||||
| Total credits of out of class work: 3.6 | Total hours of out of class work: 90 | |||||||
As: Assessable training activity Com: Training activity of compulsory overcoming (It will be essential to overcome both continuous and non-continuous assessment).
8. Evaluation criteria and Grading System
| Evaluation System | Continuous assessment | Non-continuous evaluation * | Description |
| Mid-term tests | 70.00% | 70.00% | The evaluation of the theoretical block will consist of two non-compulsory partial tests of the theoretical concepts covered in the different teaching activities. The assessment of the practical block will include attendance at the practicals, the attitude in the laboratory, the assessment of a practical questionnaire to be handed in at the end of each of the practicals, and an exam to be taken on the last day of the practicals. |
| Laboratory sessions | 20.00% | 20.00% | The laboratory sessions are compulsory activities, so that, the existence of a lack of attendance, without adequate justification, will imply that the student CANNOT pass the subject in the ordinary exam. |
| Assessment of active participation | 10.00% | 10.00% | The completion of assignments, presentation of seminars or any other activity proposed by the teacher may account for up to 10% of the grade for the course. This assessment will only be considered in the final mark if 40% of the theoretical-practical contents have been passed. |
| Total: | 100.00% | 100.00% |
According to art. 4 of the UCLM Student Evaluation Regulations, it must be provided to students who cannot regularly attend face-to-face training activities the passing of the subject, having the right (art. 12.2) to be globally graded, in 2 annual calls per subject , an ordinary and an extraordinary one (evaluating 100% of the competences).
Evaluation criteria for the final exam:
-
Continuous assessment:The ordinary exam will consist of an assessment of the theoretical knowledge acquired (theoretical block), an assessment of the laboratory practicals (practical block) and an assessment of the student's participation and achievement (participation block).
In order to pass the course, students must achieve at least 40% of the contents of the theoretical and practical blocks. The minimum grade required in all the evaluable activities of the theoretical and practical blocks will be 4.0.
The course will be considered passed when the weighted sum of the different blocks (theoretical, practical and participation) is equal to or higher than 5.0.
The theoretical block, corresponding to 70% of the total grade of the course, can be passed by means of two partial tests, which are not compulsory and can be made up. Each of them will correspond to 50% of the grade of the theoretical block. The minimum mark required to obtain the weighted average between the two tests will be 4.0.
The student who does not reach 40% of the theoretical content in the first partial test will not eliminate matter, and must reach 40% of the total content in the final test. The student who does not reach 40% of the theoretical contents in the second partial test will not be able to do media with the mark of the first partial test, even if it is higher than 4.0.
The qualification of the practical block, corresponding to 20% of the total qualification of the subject, will be determined taking into account the attendance, participation, and evaluation of the questionnaire and examination of the practical contents. The student who does not reach 40% of the content in the different evaluable activities will not be able to do media with the rest of the evaluable blocks.
The qualification of the participation block, corresponding to 10% of the total qualification of the subject, will be determined by evaluating the different activities proposed by the professor throughout the subject.
The qualification obtained in the practical block, as long as it is equal to or greater than 40%, and that obtained in the participation block will be kept for 2 academic years, as long as the student requests it.
Carrying out the different tests with unauthorized help or material will be considered fraud. In accordance with the provisions of the Student Assessment Regulations, the test in which fraud has been detected will be considered invalid and will be graded with a fail (0), including any type of detected plagiarism as a fraudulent act.
If there are any changes in the planning due to unforeseen causes, students will be notified of these changes through the virtual campus. -
Non-continuous evaluation:The ordinary call will consist of an assessment of the theoretical knowledge acquired (Theoretical Block), an assessment of the completion of laboratory practices (Practical Block) and the assessment of the participation and use of the student (Participation Block).
To pass the subject, it will be an essential requirement that the student achieve at least 40% of the contents in the theoretical and practical blocks. The minimum necessary mark in all the evaluable activities of the theoretical block and the practical block will be 4.0.
The subject will be considered approved when the weighted sum of the different blocks (theoretical, practical and participation) is equal to or greater than 5.0.
The theoretical block, corresponding to 70% of the total grade for the course, can be passed by taking two partial, non-compulsory recoverable tests. Each one of them will correspond to 50% of the qualification of the theoretical block. The minimum note necessary to be able to make the weighted average between both tests will be 4.0.
The student who does not reach 40% of the theoretical content in the first partial test will not eliminate matter, and must reach 40% of the total content in the final test. The student who does not reach 40% of the theoretical contents in the second partial test will not be able to average with the mark of the first partial test, even if it is higher than 4.0.
The qualification of the practical block, corresponding to 20% of the total qualification of the subject, will be determined taking into account the attendance, participation, and evaluation of the questionnaire and examination of the practical contents. The student who does not reach 40% of the content in the different evaluable activities will not be able to average with the rest of the blocks.
The qualification of the participation block, corresponding to 10% of the total qualification of the subject, will be determined by evaluating the different activities proposed by the professor throughout the subject.
The qualification obtained in the practical block, as long as it is equal to or greater than 40%, and that obtained in the participation block will be kept for 2 academic years, as long as the student requests it.
Carrying out the different tests with unauthorized help or material will be considered fraud. In accordance with the provisions of the Student Assessment Regulations, the test in which fraud has been detected will be considered invalid and will be graded with a fail (0), including any type of detected plagiarism as a fraudulent act.
If there are any changes in the planning due to unforeseen causes, students will be notified of these changes through the virtual campus.
Any student may change to the non-continuous evaluation modality, by the procedure established by the Center, provided that they have not participated during the period of teaching classes in evaluable activities that together account for at least 50% of the total evaluation of The subject. If a student has reached that 50% of evaluable activities or if, in any case, the class period has ended, it will be considered in continuous evaluation without the possibility of changing the evaluation modality.
Specifications for the resit/retake exam:
The extraordinary call will consist of a mandatory non-recoverable final test that will account for 90% of the final grade for the subject. The grade obtained by the student in the participation block will correspond to 10% of the final grade for the subject.
The final test will consist of a theoretical part that will mean 70% of the grade, and another practical part that will mean 20% of the final grade.
To pass the subject, it will be an essential requirement that the student achieve at least 40% of the contents in the theoretical and practical blocks.
The course will be considered approved when the weighted sum of the different blocks is equal to or greater than 5.0.
The qualification obtained in the practical block, as long as it is equal to or greater than 40%, will be kept for 2 academic years, as long as the student requests it.
Carrying out the different tests with unauthorized help or material will be considered fraud. In accordance with the provisions of article 8 of the Student Assessment Regulations, the test in which fraud has been detected will be considered invalid and will be graded with a fail (0), including any type of detected plagiarism as a fraudulent act.
The final test will consist of a theoretical part that will mean 70% of the grade, and another practical part that will mean 20% of the final grade.
To pass the subject, it will be an essential requirement that the student achieve at least 40% of the contents in the theoretical and practical blocks.
The course will be considered approved when the weighted sum of the different blocks is equal to or greater than 5.0.
The qualification obtained in the practical block, as long as it is equal to or greater than 40%, will be kept for 2 academic years, as long as the student requests it.
Carrying out the different tests with unauthorized help or material will be considered fraud. In accordance with the provisions of article 8 of the Student Assessment Regulations, the test in which fraud has been detected will be considered invalid and will be graded with a fail (0), including any type of detected plagiarism as a fraudulent act.
Specifications for the second resit / retake exam:
Only students who meet the requirements set out in the Student Assessment Regulations of the University of Castilla-La Mancha will be able to access this call. They will be evaluated according to the criteria applied in the extraordinary call.
The same criteria will be followed as for the extraordinary call of the previous course, as stated in the corresponding teaching guides (Student Assessment Regulations). This call may be used by students who are in the cases indicated in the Student Assessment Regulations in force.
The same criteria will be followed as for the extraordinary call of the previous course, as stated in the corresponding teaching guides (Student Assessment Regulations). This call may be used by students who are in the cases indicated in the Student Assessment Regulations in force.
9. Assignments, course calendar and important dates
| Not related to the syllabus/contents | |
|---|---|
| Hours | hours |
| Class Attendance (theory) [PRESENCIAL][Combination of methods] | 34.5 |
| Class Attendance (practical) [PRESENCIAL][Practical or hands-on activities] | 20 |
| Study and Exam Preparation [AUTÓNOMA][Self-study] | 82 |
| Formative Assessment [PRESENCIAL][Assessment tests] | 4 |
| Group tutoring sessions [PRESENCIAL][Group tutoring sessions] | 1.5 |
| On-line debates and forums [AUTÓNOMA][Problem solving and exercises] | 8 |
| Unit 1 (de 7): Pharmacology of the Autonomic Nervous System | |
|---|---|
| Comment: Any changes in the planning due to unforeseen causes will be notified to students through the virtual campus. |
| Global activity | |
|---|---|
| Activities | hours |
| General comments about the planning: | Detailed time planning will be available in Moodle |
10. Bibliography and Sources
