No prerequisites are established for this subject although it is recommended that the student has previously passed the subjects of Organic Chemistry I and II, Biochemistry I and II, Physical Chemistry I and II and Pharmaceutical Chemistry I.
Pharmaceutical Chemistry is the discipline responsible for the design, synthesis and development of molecules with biological activity and drugs for therapeutic purposes. In this sense, this subject is very important in the training of graduates in pharmacy. This is a subject that requires a solid previous knowledge of organic chemistry, biochemistry and physico-chemistry, and the knowledge acquired from it will be used in subjects such as pharmacology, bioinformatics, biopharmacy and pharmacokinetics, among others.
Course competences | |
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Code | Description |
B01 | Proficiency in a second foreign language at level B1 of the Common European Framework of Reference for Languages. |
B02 | Knowledge of Information and Communication Technologies (ICT). |
B03 | A correct oral and written communication |
B04 | Ethical commitment and professional deontology. |
B05 | Ability to develop those learning skills necessary to undertake further studies. |
EQ01 | Identify, design, prepare, analyse and produce active principles, drugs and other materials and products of sanitary interest. |
EQ03 | Complete standard laboratory processes including the employment of scientific equipment related to synthesis and analysis. |
EQ04 | Evaluate risks/hazards associated to the use of chemical substances and lab processes. |
G01 | Identify, design, obtain, analyze, control and produce drugs and medicines, as well as other products and raw materials of sanitary interest for human or veterinary use. |
G02 | Evaluate the therapeutic and toxic effects of substances with pharmacological activity. |
G03 | Know how to apply the scientific method and acquire skills in the handling of legislation, sources of information, bibliography, elaboration of protocols and other aspects considered necessary for the design and critical evaluation of preclinical and clinical trials. |
G04 | Design, prepare, supply and dispense medicines and other products of health interest. |
G05 | Provide therapeutic advice in pharmacotherapy and dietotherapy, as well as in the nutritional and food field in the establishments where they provide services. |
G06 | Promote the rational use of medicines and medical devices, as well as to acquire basic knowledge in clinical management, health economics and the efficient use of health resources. |
G07 | Identify, evaluate and assess problems related to drugs and medicines, as well as participate in pharmacovigilance activities. |
G08 | Conducting clinical and social pharmacy activities, following the pharmaceutical care cycle. |
G09 | Intervene in health promotion and disease prevention activities at the individual, family and community levels, with an integral and multi-professional vision of the health-disease process. |
G10 | Design, apply and evaluate clinical reagents, methods and analytical techniques, knowing the basic principles of clinical analysis and the characteristics and contents of laboratory diagnostic reports. |
G11 | Evaluate the toxicological effects of substances and design and apply appropriate tests and trials. |
G12 | Develop hygienic-sanitary analyses, especially those related to food and environment. |
G13 | Develop communication and information skills, both oral and written, to deal with patients and users of the centre where they carry out their professional activity. Promote the capacity to work and collaborate with multidisciplinary teams and those related to other health professionals. |
G14 | Know the ethical and deontological principles according to the legislative, regulatory and administrative provisions governing professional practice, understanding the ethical implications of health in a changing social context. |
G15 | Recognise own limitations and the need to maintain and update professional competence, with particular emphasis on self-learning of new knowledge based on scientific evidence. |
T01 | Critical thinking skills based on the application of the scientific method |
T02 | Ability to manage quality scientific information, bibliography, specialized databases and resources accessible through the Internet. |
T03 | Handling of basic and specific software for the treatment of information and experimental results. |
T04 | Motivation for quality, safety at work and awareness of environmental issues, with knowledge of the internationally recognised systems for the correct management of these aspects. |
T05 | Organizational, planning and implementation skills. |
T06 | Ability to address human resources decision-making and management. |
T07 | Ability to work as a team and, where appropriate, exercise leadership functions, encouraging entrepreneurship. |
T08 | Develop interpersonal skills and the ability to function in an international and multicultural context. |
Course learning outcomes | |
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Description | |
Acquisition of basic skills in synthesis and analytical characterization of drugs in a practical level. | |
Ability to find and analyze scientific information regarding the chemical aspects of drugs. | |
ability to associate the structure of drugs with their mechanism of action and their therapeutic activity at the molecular level. | |
ability to define the pharmacophore group of a set of active molecules. | |
ability to design synthetic routes to prepare drugs | |
ability to propose chemical transformations of drugs aimed at optimizing their pharmacokinetic properties and their biological activity. | |
ability to predict the metabolic transformations suffered by drugs inside the body. | |
ability to name drugs and to represent their structure from the systematic nomenclature | |
Additional outcomes | |
Not established. |
Training Activity | Methodology | Related Competences (only degrees before RD 822/2021) | ECTS | Hours | As | Com | Description | |
Class Attendance (theory) [ON-SITE] | Combination of methods | B01 B02 B03 B04 B05 G01 G02 G03 G04 G05 G06 G07 G08 G09 G10 G11 G12 G13 G14 G15 T01 T02 T03 T04 T05 T06 T07 T08 | 0.92 | 23 | Y | N | The teaching resources will be available on the Moodle platform before the beginning of the activities. In addition, students will have access to complementary bibliographic and audiovisual material on this platform. On the other hand, the recommended bibliography is available in the university library of the Albacete campus. After the exposition of the topics in class (expository method) by the professor, the active participation of the student through cooperative work, both in the classroom and outside it, and in the resolution of problems and seminars that will be carried out actively during the course will be taken into account in the final evaluation of the student's participation in the subject. This participation will consist of the elaboration of seminars and case studies, and activities consisting of short review questions, which will be distributed throughout the different theoretical expositions, complemented with examples or specific cases from the recent bibliography that put in context the current relevance of each topic. Another aspect to consider in this assessment will be the preparation of a non-compulsory evaluable work whose deadline for delivery will be the day of the exam of the ordinary call. | |
Class Attendance (practical) [ON-SITE] | Practical or hands-on activities | B01 B02 B03 B04 B05 EQ01 EQ03 EQ04 G01 G02 G03 G04 G05 G06 G07 G08 G09 G10 G11 G12 G13 G14 G15 T01 T02 T03 T04 T05 T06 T07 T08 | 0.8 | 20 | Y | Y | Practical teaching will be given in small groups within periods established in the academic calendar that do not coincide with other teaching activities. They will be carried out in the laboratories, all of them equipped with the appropriate means to achieve the proposed objectives. These activities are MANDATORY and NOT RECOVERABLE so the student will not be able to pass the course if they are not carried out properly. | |
Workshops or seminars [ON-SITE] | Combination of methods | B01 B02 B03 B04 B05 G01 G02 G03 G04 G05 G06 G07 G08 G09 G10 G11 G12 G13 G14 G15 T01 T02 T03 T04 T05 T06 T07 T08 | 0.52 | 13 | Y | N | The resolution of these seminars and the participation in them with proposals, questions, or examples, will constitute an important part of the PARTICIPATION block. | |
Study and Exam Preparation [OFF-SITE] | Self-study | B01 B02 B03 B04 B05 G01 G02 G03 G04 G05 G06 G07 G08 G09 G10 G11 G12 G13 G14 G15 T01 T02 T03 T04 T05 T06 T07 T08 | 2.07 | 51.75 | Y | N | The student may request personal tutoring on the contents of the course by previously arranging a meeting with the professor. | |
Study and Exam Preparation [OFF-SITE] | Problem solving and exercises | B01 B02 B03 B04 B05 G01 G02 G03 G04 G05 G06 G07 G08 G09 G10 G11 G12 G13 G14 G15 T01 T02 T03 T04 T05 T06 T07 T08 | 1.53 | 38.25 | Y | N | The student may request personal tutoring on the contents of the course by previously arranging a meeting with the professor. | |
Formative Assessment [ON-SITE] | Assessment tests | B01 B02 B03 B04 B05 G01 G02 G03 G04 G05 G06 G07 G08 G09 G10 G11 G12 G13 G14 G15 T01 T02 T03 T04 T05 T06 T07 T08 | 0.16 | 4 | Y | Y | Specific dates have been set aside in the academic calendar for evaluation tests that do not coincide with other academic activities. | |
Total: | 6 | 150 | ||||||
Total credits of in-class work: 2.4 | Total class time hours: 60 | |||||||
Total credits of out of class work: 3.6 | Total hours of out of class work: 90 |
As: Assessable training activity Com: Training activity of compulsory overcoming (It will be essential to overcome both continuous and non-continuous assessment).
Evaluation System | Continuous assessment | Non-continuous evaluation * | Description |
Assessment of active participation | 10.00% | 10.00% | |
Test | 70.00% | 70.00% | |
Laboratory sessions | 20.00% | 20.00% | |
Total: | 100.00% | 100.00% |
Not related to the syllabus/contents | |
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Hours | hours |
Class Attendance (theory) [PRESENCIAL][Combination of methods] | 23 |
Class Attendance (practical) [PRESENCIAL][Practical or hands-on activities] | 20 |
Workshops or seminars [PRESENCIAL][Combination of methods] | 13 |
Study and Exam Preparation [AUTÓNOMA][Self-study] | 51.75 |
Study and Exam Preparation [AUTÓNOMA][Problem solving and exercises] | 38.25 |
Formative Assessment [PRESENCIAL][Assessment tests] | 4 |
Global activity | |
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Activities | hours |