1. General information
Course:
BIOCHEMISTRY II AND IMMUNOLOGY
Code:
34311
Type:
CORE COURSE
ECTS credits:
9
Degree:
332 - UNDERGRADUATE DEGREE PROGRAMME IN MEDICINE
Academic year:
2023-24
Center:
9 - FACULTY OF MEDICINE OF CIUDAD REAL
Group(s):
20
Year:
2
Duration:
AN
Main language:
Spanish
Second language:
Use of additional languages:
English Friendly:
Y
Web site:
https://www.uclm.es/ciudad-real/medicina
Bilingual:
N
Lecturer:
JOSE LUIS ALBASANZ HERRERO
- Group(s):
20
Building/Office
Department
Phone number
Email
Office hours
Facultad de Medicina CR/2.01
QUÍMICA INORG., ORG., Y BIOQ.
926295237
jose.albasanz@uclm.es
Monday, Wednesday and Friday from 16.00 to 18.00. Request by email.
Lecturer:
INMACULADA BALLESTEROS YAÑEZ
- Group(s):
20
Building/Office
Department
Phone number
Email
Office hours
Facultad de Medicina/2.20/Decanato
QUÍMICA INORG., ORG., Y BIOQ.
926926 052244
inmaculada.byanez@uclm.es
Tuesday and Thursday from 16.00 to 19.00. Out of this schedule, request by email.
Lecturer:
CARMEN MARIA CABRERA MORALES
- Group(s):
20
Building/Office
Department
Phone number
Email
Office hours
CIENCIAS MÉDICAS
Carmen.Cabrera@uclm.es
Lecturer:
JOSE MIGUEL URRA ARDANAZ
- Group(s):
20
Building/Office
Department
Phone number
Email
Office hours
Facultad de Medicina/1.31
CIENCIAS MÉDICAS
josemiguel.urra@uclm.es
2. Pre-Requisites
Referring to the Prerequisite and Incompatibility Table of the Medicine Degree Study Plan: "It is necessary to have passed the subjects of Biochemistry I and Biology in order to pass this subject."
3. Justification in the curriculum, relation to other subjects and to the profession
The subject "Biochemistry II and Immunology" belongs to Module I (Morphology, Structure and Function of the Human Body) and to Subject 1.1 (Development, Structure and Function of the Healthy Human Body at the Molecular and Cellular Level) of the Medicine Teaching Plan. It is a mandatory annual subject, with 9 ECTS, and it is taught during the second year.
Biochemistry and Immunology are two of the most dynamic disciplines of Biology and are indispensable for understanding other disciplines of the Medicine Degree, such as Physiology, Human Genetics, Pharmacology, Nutrition, etc. In addition to explaining the chemical functioning of living matter under healthy conditions, Biochemistry and Immunology have greatly contributed to the development of modern scientific medicine, by identifying the molecular bases of many pathological processes and the mechanism of action of drugs. For all these reasons, the subject Biochemistry II and Immunology represents an essential element of the basic training of the future doctor.
The content and resources of each module will be provided through the Moodle platform.
4. Degree competences achieved in this course
| Course competences | |
|---|---|
| Code | Description |
| 1.1 | Knowledge of cell structure and function. |
| 1.10 | Information, expression and gene regulation. |
| 1.11 | Inheritance. |
| 1.13 | To know the morphology, structure and function of the skin, blood, circulatory, digestive, locomotor, reproductive, excretory and respiratory apparatus and systems; endocrine system, immune system and central and peripheral nervous system. |
| 1.15 | Homeostasis |
| 1.17 | Handling basic laboratory material and techniques. |
| 1.18 | Interpret a normal blood test. |
| 1.19 | Recognize with macroscopic and microscopic methods and imaging techniques the morphology and structure of tissues, organs and systems. |
| 1.2 | Biomolecules. |
| 1.3 | Metabolism. |
| 1.4 | Metabolic regulation and integration. |
| 1.5 | To know the basic principles of human nutrition. |
| 1.6 | Cellular communication. |
| 1.7 | Excitable membranes. |
| 1.8 | Cell cycle. |
| 1.9 | Cell differentiation and proliferation. |
| CT01 | Proficiency in a second foreign language at level B1 of the Common European Framework of Reference for Languages. |
| CT03 | Good oral and written communication skills. |
| G07 | Understand and recognize the normal structure and function of the human body, at the molecular, cellular, tissue, organic and system levels, in the different stages of life and in both sexes. |
| G11 | Understand and recognize the effects of growth, development and aging on the individual and their social environment. |
| G36 | To be able to formulate hypotheses, collect and critically evaluate information for problem solving, following the scientific method. |
| G37 | To acquire the basic training for research activity. |
5. Objectives or Learning Outcomes
| Course learning outcomes | |
|---|---|
| Description | |
| Learning to design and organize the work. Acquiring habits of perseverance in the study. | |
| Acquisition of oral and/or written presentation and communication skills. | |
| To know the cellular structure and function. Biomolecules. Metabolism. Metabolic regulation and integration. To know the basic principles of human nutrition. Cell communication. Excitable membranes. Cell cycle. Cell differentiation and proliferation. Gene information, expression and regulation. Inheritance. Embryonic development and organogenesis. Homeostasis. Adaptation to the environment. | |
| Handling basic laboratory material and techniques. Interpret a normal blood test. Recognize with macroscopic and microscopic methods and imaging techniques the morphology and structure of tissues. Perform functional tests, determine vital parameters and interpret them. Basic physical examination. | |
| Additional outcomes | |
| Not established. |
6. Units / Contents
-
Unit 1: Introducción al metabolismo. Bioenergética y Señalización
-
Unit 2: Metabolismo intermediario.
-
Unit 3: Metabolismo de glúcidos.
-
Unit 4: Metabolismo de lípidos.
-
Unit 5: Metabolismo de aminoácidos y bases nitrogenadas.
-
Unit 6: Integración del metabolismo y Nutrición.
-
Unit 7: Inmunidad Innata.
-
Unit 8: Reconocimiento de antígenos por receptores de células B y de células T.
-
Unit 9: Comunicación celular en el sistema inmune.
-
Unit 10: Dinámica de la inmunidad adaptativa.
7. Activities, Units/Modules and Methodology
| Training Activity | Methodology | Related Competences (only degrees before RD 822/2021) | ECTS | Hours | As | Com | Description | |
| Class Attendance (practical) [ON-SITE] | Practical or hands-on activities | 0.9 | 22.5 | Y | Y | Practices, workshops, seminars | ||
| Class Attendance (theory) [ON-SITE] | Lectures | 0.9 | 22.5 | Y | N | Lectures | ||
| Final test [ON-SITE] | Assessment tests | 0.12 | 3 | Y | Y | PEM (test questions) and PRAC (open questions) questions | ||
| Progress test [ON-SITE] | Assessment tests | 0.18 | 4.5 | Y | Y | PEM (test questions) and PRAC (open questions) questions | ||
| Project or Topic Presentations [ON-SITE] | Problem solving and exercises | 0.9 | 22.5 | Y | Y | Individual or Group work presentations | ||
| Problem solving and/or case studies [ON-SITE] | Problem solving and exercises | 0.6 | 15 | Y | Y | Clinical case and problem resolution | ||
| Writing of reports or projects [OFF-SITE] | Group Work | 0.36 | 9 | Y | N | |||
| Study and Exam Preparation [OFF-SITE] | Self-study | 3.84 | 96 | Y | N | self-study | ||
| Other off-site activity [OFF-SITE] | Self-study | 1.2 | 30 | Y | N | Analysis, preparation and study of practical scripts (autonomous activity). Case study Self-learning Independent work | ||
| Total: | 9 | 225 | ||||||
| Total credits of in-class work: 3.6 | Total class time hours: 90 | |||||||
| Total credits of out of class work: 5.4 | Total hours of out of class work: 135 | |||||||
As: Assessable training activity Com: Training activity of compulsory overcoming (It will be essential to overcome both continuous and non-continuous assessment).
8. Evaluation criteria and Grading System
| Evaluation System | Continuous assessment | Non-continuous evaluation * | Description |
| Final test | 20.00% | 70.00% | |
| Progress Tests | 50.00% | 0.00% | |
| Theoretical papers assessment | 5.00% | 5.00% | |
| Laboratory sessions | 20.00% | 20.00% | |
| Assessment of active participation | 5.00% | 5.00% | |
| Total: | 100.00% | 100.00% |
According to art. 4 of the UCLM Student Evaluation Regulations, it must be provided to students who cannot regularly attend face-to-face training activities the passing of the subject, having the right (art. 12.2) to be globally graded, in 2 annual calls per subject , an ordinary and an extraordinary one (evaluating 100% of the competences).
Evaluation criteria for the final exam:
-
Continuous assessment:Evaluation criteria for the ordinary call:
¿ Continuous assessment:
A student enrolled for the first time in a subject is entitled to two calls during the academic year:
1. Ordinary call: it comprises the continuous evaluation of all theoretical and practical activities reflected in the timetable attending to the conditions described in the teaching guide of the subject and the minimum attendance requirements to pass the subject.
2. Extraordinary call: It includes the evaluation exclusively of the failed part of the subject in the ordinary call. It consists of a theoretical exam and/or a practical exam. The rest of the marks of the practical part will be those obtained during the course in reports, seminars, presentations, assignments, participation and attitude or OSCE.
In case of failing the course the first time it is taken, for the following academic year there will be two of this three options:
1. Ordinary call: within this call, two modalities can be chosen:
a. Attendance mode: It includes the continuous evaluation of all theoretical and practical activities reflected in the timetable, complying with the conditions described in the teaching guide of the subject, as if the subject was taken for the first time. Thus, the grades obtained in the previous year will not be taken into account.
b. Non-attendance mode: It includes the evaluation of only the failed part of the subject in the previous course through a theoretical exam and/or a practical exam per semester on the same date as the final exam of each semester. The marks for practical exams other than the practical exam will be kept from the previous course. This modality can only be chosen in the case of having taken the subject in the ordinary call in the previous academic year.
2. Extraordinary call: It includes the evaluation of only the failed part of the subject in the ordinary call either of the current academic year, if the student has chosen the ordinary on-site call, or of the previous academic year, in the rest of the cases. It will consist of a theoretical and/or a practical exam. The rest of the marks of the practical part will be those of the current or previous course. In the case of not having taken the ordinary on-site exam in the current or previous academic year, the grades of previous exams will not be taken into account, since only one course will be kept.
3. Special final exam: This includes the evaluation of only the failed part of the subject in the previous academic year. This call can only be requested in key subjects. It will consist of a theoretical exam and/or a practical exam. The rest of the marks of the practical part will be those of the previous course. In the case of not having taken the ordinary on-site exam in the current or previous course, the grades of previous exams will not be taken into account since only one course will be kept.
These conditions will only be maintained in the academic year consecutive to the ordinary on-site call of a subject. The grade of the practical or theoretical part passed will only be kept if the minimum attendance requirements to pass the subject described in the electronic guide have been met.
If the subject is not passed in the second academic year, the same biannual cycle criteria described for the first and second year of enrollment will be followed in the third and successive odd numbered years of enrollment.
ORDINARY CALL:
Theoretical evaluation:
70% distributed in:
- 50% module exams
- 20% final semester exams
To pass the course it will be necessary to obtain 40% of this 70%, which means, at least, 2.8 points in the theoretical part of the 10 total points of the course and to fulfill the requirements of the section "Evaluation criteria".
For the module exams (50% of the grade, i.e. 5 points) no minimum grade is established, so all grades obtained will be added together.
For the final exams (20% of the grade, i.e. 2 points) a minimum grade equal to 40% of the maximum grade to be achieved in each final exam is established. In order to favor the weight of the continuous evaluation in the final grade, not reaching the minimum grade established will not mean the impossibility to pass the course, but the points of that final exam will not be added to the rest of the points obtained.
Evaluation of practices, presentations, problems, assignments, participation and attitude:
30% valued jointly as follows for basic subjects:
- Practical exams at the end of the semester: 15%.
- Presentations, papers and practices: 10%.
- Participation and attitude: 5%.
30% evaluated jointly as follows for clinical subjects from 3rd to 5th year:
- OSCE (Objective Structured Clinical Evaluation): 15%
- Practical exam: 10%.
- Participation and attitude: 5%.
To pass the course it will be necessary to obtain 40% of the 30%, which represents at least 1.2 points in the practical part of the 10 total points of the course and to fulfill the requirements of the section "Evaluation Criteria" that appears in the electronic guide.
The indispensable requirement for the student to be able to take the OSCE test in a course is to be enrolled in at least 75% of the subjects of that course that participate in this OSCE. test. Otherwise, an alternative practical test will be given independently for each subject.
EXTRAORDINARY CALL, SPECIAL FINAL CALL, ORDINARY NON-ATTENDANCE CALL:
Theoretical evaluation: exam with a weight of 70%. To pass the course it will be necessary to obtain 40% of this 70%, which means at least 2.8 points in the theoretical part of the 10 total points of the course and meet the requirements of the section "Evaluation criteria". In case of having passed the theoretical part of the course in the current or previous year, the grade obtained in the last exam will be maintained.
Practical evaluation: to pass the course it will be necessary to obtain 40% of the 30%, which means at least 1.2 points in the practical part of the 10 total points of the course and to fulfill the requirements of the section "Evaluation criteria". In case of having passed the practical part in the current or previous course, the grade obtained in the last exam will be maintained.
There will be a Practice Exam and the results obtained in the OSCE of the previous ordinary on-site exam, either of the current or previous year, will be taken into account.
- Non-continuous evaluation:
See what is described in the previous point.
Particularities of the extraordinary call:
See what is described in the previous point.
Particularities of the special final call:
See what is described in the previous point. -
Non-continuous evaluation:See above.
Specifications for the resit/retake exam:
See above.
Specifications for the second resit / retake exam:
See above.
9. Assignments, course calendar and important dates
| Not related to the syllabus/contents | |
|---|---|
| Hours | hours |
| Class Attendance (practical) [PRESENCIAL][Practical or hands-on activities] | 22.5 |
| Class Attendance (theory) [PRESENCIAL][Lectures] | 22.5 |
| Final test [PRESENCIAL][Assessment tests] | 3 |
| Progress test [PRESENCIAL][Assessment tests] | 4.5 |
| Project or Topic Presentations [PRESENCIAL][Problem solving and exercises] | 22.5 |
| Problem solving and/or case studies [PRESENCIAL][Problem solving and exercises] | 15 |
| Writing of reports or projects [AUTÓNOMA][Group Work] | 9 |
| Study and Exam Preparation [AUTÓNOMA][Self-study] | 96 |
| Other off-site activity [AUTÓNOMA][Self-study] | 30 |
| Unit 1 (de 10): Introducción al metabolismo. Bioenergética y Señalización | |
|---|---|
| Group 20: | |
| Initial date: 11-09-2023 | End date: 29-09-2023 |
| Comment: see schedule in the web | |
| Unit 2 (de 10): Metabolismo intermediario. | |
|---|---|
| Group 20: | |
| Initial date: 02-10-2023 | End date: 19-10-2023 |
| Comment: see schedule in the web | |
| Unit 3 (de 10): Metabolismo de glúcidos. | |
|---|---|
| Group 20: | |
| Initial date: 23-10-2023 | End date: 10-11-2023 |
| Comment: see schedule in the web | |
| Unit 4 (de 10): Metabolismo de lípidos. | |
|---|---|
| Group 20: | |
| Initial date: 13-11-2023 | End date: 30-11-2023 |
| Comment: see schedule in the web | |
| Unit 5 (de 10): Metabolismo de aminoácidos y bases nitrogenadas. | |
|---|---|
| Activities | Hours |
| Class Attendance (practical) [PRESENCIAL][Practical or hands-on activities] | 2.25 |
| Class Attendance (theory) [PRESENCIAL][Lectures] | 2.25 |
| Final test [PRESENCIAL][Assessment tests] | .3 |
| Progress test [PRESENCIAL][Assessment tests] | .45 |
| Project or Topic Presentations [PRESENCIAL][Problem solving and exercises] | 2.25 |
| Problem solving and/or case studies [PRESENCIAL][Problem solving and exercises] | 1.5 |
| Writing of reports or projects [AUTÓNOMA][Group Work] | .9 |
| Study and Exam Preparation [AUTÓNOMA][Self-study] | 9.6 |
| Other off-site activity [AUTÓNOMA][Self-study] | 3 |
| Group 20: | |
| Initial date: 04-12-2023 | End date: 22-12-2023 |
| Comment: see schedule in the web | |
| Unit 6 (de 10): Integración del metabolismo y Nutrición. | |
|---|---|
| Group 20: | |
| Initial date: 29-01-2024 | End date: 16-02-2024 |
| Comment: see schedule in the web | |
| Unit 7 (de 10): Inmunidad Innata. | |
|---|---|
| Group 20: | |
| Initial date: 19-02-2024 | End date: 8-03-2024 |
| Comment: see schedule in the web | |
| Unit 8 (de 10): Reconocimiento de antígenos por receptores de células B y de células T. | |
|---|---|
| Group 20: | |
| Initial date: 11-03-2024 | End date: 05-04-2024 |
| Comment: see schedule in the web | |
| Unit 9 (de 10): Comunicación celular en el sistema inmune. | |
|---|---|
| Group 20: | |
| Initial date: 08-04-2024 | End date: 26-04-2024 |
| Comment: see schedule in the web | |
| Unit 10 (de 10): Dinámica de la inmunidad adaptativa. | |
|---|---|
| Group 20: | |
| Initial date: 29-04-2024 | End date: 17-05-2024 |
| Comment: see schedule in the web | |
| Global activity | |
|---|---|
| Activities | hours |
10. Bibliography and Sources