It is recommended to have passed the ground level course “Química” and to be enrolled in the course “Química Orgánica I”
The course “Química Orgánica II” is included in the module of Fundamentals of Chemistry in the Degree of Chemistry. It is designed to develop the concepts and fundamental data of Organic Chemistry. Lessons also show the experimental evidence that supports the main organic chemistry concepts, and to apply these data and concepts to the resolution of chemical problems. The course also points to the rapid evolution of this area and how it plays as a key role in modern technological developments in very diverse fields, from biology to materials science, influencing in a fundamental way all aspects of daily life.
“Química Orgánica II” is a compulsory, semester-long course, taught in the second year, which introduces the fundamentals of the different areas of chemistry. It consists of 6 theoretical credits. It could be considered as the second part of “Química Orgánica I”, and it is devoted to study the reactivity of the different functional groups, showing the main reaction mechanisms of the main types of organic compounds. At the same time, it tries to generate in the students the capacity to value the importance of Organic Chemistry in their daily life.
Course competences | |
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Code | Description |
CB02 | Apply their knowledge to their job or vocation in a professional manner and show that they have the competences to construct and justify arguments and solve problems within their subject area. |
E01 | Understand and use chemical terminology, nomenclature, conventions and units |
E02 | Deduce the variation of the properties of the chemical elements according to the Periodic Table |
E03 | Handle chemicals safely and with respect to the environment |
E05 | Know the chemical elements and their compounds, their forms of obtaining, structure, properties and reactivity, as well as the main techniques for their analysis |
E06 | Know the structural properties of chemical compounds, including stereochemistry, as well as the main structural research techniques |
E07 | Relate macroscopic properties with those of atoms, molecules and non-molecular chemical compounds |
E09 | Know the kinetics of chemical change, including catalysis and reaction mechanisms |
E15 | Know how to handle the standard chemical instrumentation and be able to elaborate and manage standardized procedures of work in the laboratory and chemical industry |
E16 | Plan, design and develop projects and experiments |
E17 | Develop the ability to relate to each other the different specialties of Chemistry, as well as this one with other disciplines (interdisciplinary character) |
G01 | Know the principles and theories of Chemistry, as well as the methodologies and applications characteristic of analytical chemistry, physical chemistry, inorganic chemistry and organic chemistry, understanding the physical and mathematical bases that require |
G02 | Be able to gather and interpret data, information and relevant results, obtain conclusions and issue reasoned reports on scientific, technological or other problems that require the use of chemical tools |
G03 | Know how to apply the theoretical-practical knowledge acquired in the different professional contexts of Chemistry |
G04 | Know how to communicate, orally and in writing, the knowledge, procedures and results of chemistry, both specialized and non-specialized |
G05 | Acquire and adapt new knowledge and techniques of any scientific-technical discipline with incidence in the chemical field |
T03 | Proper oral and written communication |
T06 | Ability to approach decision making |
T07 | Ability to work as a team and, where appropriate, exercise leadership functions, fostering the entrepreneurial character |
T09 | Motivation for quality, job security and awareness of environmental issues, with knowledge of internationally recognized systems for the correct management of these aspects |
T10 | Ability to use specific software for chemistry at user level |
T11 | Ability to obtain bibliographic information, including Internet resources |
Course learning outcomes | |
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Description | |
Know the main aspects of the terminology and nomenclature in Organic Chemistry | |
Recognize the main reactive intermediates and the influence of stereoelectronic effects on their stability and reactivity | |
Know how to apply the knowledge of Organic Chemistry to the solution of synthetic and structural problems | |
Know the basic principles of Organic Chemistry. | |
To ensure that the student is able to search and select information in the field of Organic Chemistry and that he / she is capable of processing and presenting it adequately both orally and in writing, developing his / her synthesis capacity, being critical and objective | |
To develop in the student the capacity of initiative to pose and solve concrete problems of Organic Chemistry, as well as to interpret the obtained results | |
Develop your ability to work as a team. | |
Acquire an awareness of environmental protection developing the idea that Organic Chemistry should be used to improve the quality of life. | |
Know the stereochemistry of organic compounds and the stereoselectivity of the main reactions. | |
Know the structure of the main organic functional groups | |
Know the utility of the spectroscopic techniques in Organic Chemistry | |
Additional outcomes | |
Not established. |
Training Activity | Methodology | Related Competences (only degrees before RD 822/2021) | ECTS | Hours | As | Com | Description | |
Class Attendance (theory) [ON-SITE] | Lectures | CB02 E01 E03 E06 E07 E09 E15 G01 G02 G03 G05 | 1.16 | 29 | N | N | Face-to-face teaching theoretical classes and resolution of examples | |
Problem solving and/or case studies [ON-SITE] | Guided or supervised work | E01 E07 T03 T07 T09 T11 | 0.96 | 24 | Y | N | Resolution of exercises and case studies | |
Study and Exam Preparation [OFF-SITE] | Self-study | CB02 E01 E02 E07 G01 G02 | 2.72 | 68 | N | N | Continuous study for the realization of the seminars and the understanding of the subject. | |
Progress test [ON-SITE] | Assessment tests | E01 E07 T03 T07 T09 T11 | 0.08 | 2 | Y | N | In this activity, the student must demonstrate that he is acquiring, progressively, the basic concepts of Organic Chemistry. | |
Final test [ON-SITE] | Assessment tests | E01 E07 T03 T07 T09 T11 | 0.08 | 2 | Y | Y | In this test, the student must demonstrate their knowledge of Organic Chemistry. | |
Study and Exam Preparation [OFF-SITE] | Self-study | CB02 E06 E07 E09 E17 G01 G02 G03 G05 T03 | 1 | 25 | N | N | Preparation of evaluations | |
Total: | 6 | 150 | ||||||
Total credits of in-class work: 2.28 | Total class time hours: 57 | |||||||
Total credits of out of class work: 3.72 | Total hours of out of class work: 93 |
As: Assessable training activity Com: Training activity of compulsory overcoming (It will be essential to overcome both continuous and non-continuous assessment).
Evaluation System | Continuous assessment | Non-continuous evaluation * | Description |
Final test | 65.00% | 100.00% | The final grade of the exam may be increased as a result of the dedication in the criterion "resolution of problems or cases" |
Assessment of problem solving and/or case studies | 15.00% | 0.00% | The student's participation in solving problems in class will be assessed and will account for 15% of the final mark. |
Progress Tests | 20.00% | 0.00% | Students who choose the continuous evaluation will have to take a first test of 2 hours towards the middle of the subject. Students who achieve a grade equal to or higher than 4 points will be able to take a second test, coinciding with the final exam. This test will include the knowledge worked in the second part of the course, although, given the nature of the subject, it will be necessary to use the knowledge acquired in the first part to pass this second test. It will be necessary to achieve a score equal to or higher than 4 points to be able to average with the first test. Those students who achieve a mark equal to or higher than 5 points on average, considering the marks of both exams and the resolution of problems and cases, will pass the course in the ordinary exam. Students who have not passed the first exam must take the final exam, which includes the complete subject matter. |
Total: | 100.00% | 100.00% |
Not related to the syllabus/contents | |
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Hours | hours |
Study and Exam Preparation [AUTÓNOMA][Self-study] | 68 |
Progress test [PRESENCIAL][Assessment tests] | 2 |
Final test [PRESENCIAL][Assessment tests] | 2 |
Study and Exam Preparation [AUTÓNOMA][Self-study] | 25 |
Unit 1 (de 14): ALKYL HALIDES. Classification and nomenclature. Physical properties. Preparation by alkane halogenation: mechanism. Regioselectivity. Allylic halogenation. Synthesis from alcohols | |
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Activities | Hours |
Class Attendance (theory) [PRESENCIAL][Lectures] | 2 |
Problem solving and/or case studies [PRESENCIAL][Guided or supervised work] | 1 |
Unit 2 (de 14): REACTIVITY OF ALKYL HALIDES: Influencing factors on SN2 reaction rate. Unimolecular substitution reaction (SN1). Stereochemistry and kinetics. Mechanism. Influencing factors on SN1 reaction rate. Elimination reactions on alkyl halides. E2 and E1 mechanisms: kinetics, approaches, and stereochemistry. Influencing factors on elimination. Substitution-elimination competition. | |
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Activities | Hours |
Class Attendance (theory) [PRESENCIAL][Lectures] | 3 |
Problem solving and/or case studies [PRESENCIAL][Guided or supervised work] | 3 |
Unit 3 (de 14): ARYL HALIDES. Origin, bonds, physical properties. Reactions of aryl halides. Nucleophilic susbstitution on aryl halides: addition-elimination mechanism. Related nucleophilic substitution reactions. Elimination-addition mechanism. Benzyne. Diels-Alder reaction on benzyne. | |
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Activities | Hours |
Class Attendance (theory) [PRESENCIAL][Lectures] | 1 |
Problem solving and/or case studies [PRESENCIAL][Guided or supervised work] | 2 |
Unit 4 (de 14): ORGANOMETALLIC COMPOUNDS. Carbon-Metal bonds in organometallic compounds. Nomenclature. Organolithium compounds. Grignard¿s reagents. Organolithium and organomagnesium compounds as Brønsted¿s bases. Synthesis of aliphatic and acetylenic alcohols. Alkane synthesis by using organocopper compounds. Simmons-Smith reation: Carbenes and carbenoids. | |
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Activities | Hours |
Class Attendance (theory) [PRESENCIAL][Lectures] | 2 |
Problem solving and/or case studies [PRESENCIAL][Guided or supervised work] | 1 |
Unit 5 (de 14): ALCOHOLS, DIOLS Y THIOLS. Nomenclature. Structure ans physical properties. Hydrogen bonds. Spectroscopic features of alcohols. Origin of alcohols. Fuentes de alcoholes. Synthesis of alcohols: Reduction of aldehydes, ketones, carboxilic acids and esters. Alcohols from epoxides. Synthesis of diols. Acidity of alcohols. Alcoxides preparation. Reactivity of alcohols: ether synthesis. Esterification. Oxidation. Oxidative rupture of vicinal diols. Dehydration of alcohol. Alkyl halides from alcohols. Thiols: synthesis, physical and chemical properties. | |
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Activities | Hours |
Class Attendance (theory) [PRESENCIAL][Lectures] | 2 |
Problem solving and/or case studies [PRESENCIAL][Guided or supervised work] | 2 |
Unit 6 (de 14): PHENOLS. Nomenclature. Bond and structure. Physical properties. Spectroscopic features of phenols. Synthetic and natural origin of phenols. Acidity: substitution effects. Phenol reactivity: aromatic electrophilic substitutuion. Acylation of phenols Aspirine: carboxylation of phenols, Kolbe -Schmitt reaction. Preparation of arylethers. Oxidation of phenols: quinones. | |
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Activities | Hours |
Class Attendance (theory) [PRESENCIAL][Lectures] | 1 |
Problem solving and/or case studies [PRESENCIAL][Guided or supervised work] | 1 |
Unit 7 (de 14): ETHERS, EPOXIDES AND SULFURES. Nomenclature. Bond and structure. Physical properties. Spectroscopic features of ethers. Crown-ethers. Synthesis of ethers. Reactivity: acid-catalysed bond rupture. Rupture of aryl ethers by hydracids. Claisen rearrangement of alylaryl ethers. Synthesis of epoxides. Reactions: basic and acid catalysed ring opening. Biological processes involving epoxides. Synthesis of sulfures. Oxidation: sulfoxides and sulfones. Alkylation of sulfures: sulfonium salts. | |
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Activities | Hours |
Class Attendance (theory) [PRESENCIAL][Lectures] | 2 |
Problem solving and/or case studies [PRESENCIAL][Guided or supervised work] | 1 |
Unit 8 (de 14): AMINES AND NITROGEN DERIVATIVES. Nomenclature. Bond and structure. Physical properties. Spectroscopic features of amines. Basicity. Tetraalkylammonium salt as phase transfer catalysis agents. Preparation of amines: ammonia alkylation, Gabriel¿s synthesis, reductions yielding amines, reductive amination. Hofmann¿s rearrangement. Reactivity: N-alkylation, Hofmann¿s elimination, N-acylation, aromatic electrophilic substitution on anilines, nitrosation of alkyl- and arylamines, substitution on diazonium salts, diazonium salts as electrophiles. Nitrocompounds. Nitro-aci tautomerism. Synthesis of nitrocompunds. ¿-H acidity. Nef¿s reaction. Reduction. | |
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Activities | Hours |
Class Attendance (theory) [PRESENCIAL][Lectures] | 4 |
Problem solving and/or case studies [PRESENCIAL][Guided or supervised work] | 3 |
Unit 9 (de 14): ALDEHYDES AND KETONES. NUCLEOPHILIC ADDITION TO CARBONYL GROUP. Nomenclature. Bond and structure: carbonyl group. Physical properties. Spectroscopic features of aldehydes and ketones. Origin and Synthesis of aldehydes and ketones. Reactivity: nucleophilic addition to carbonyl group. Reaction with: water and alcohols. Ketals as protecting groups. Reaction with hydrogen cyanide. Reaction with Grignard¿s reagents. Reaction with primary amines: nuclephilic addition-elimination. Reaction with secondary amine: enamines. Reaction with hydroxylamine: oximes. Beckmann¿s rearrangement. Reaction with hydrazine; hydrazones. Wittig¿s reaction. Oxidation of aldehydes. Baeyer-Villiger¿s oxidation of ketones. Reduction of aldehydes and ketones. Cannizaro¿s reaction. | |
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Activities | Hours |
Class Attendance (theory) [PRESENCIAL][Lectures] | 3 |
Problem solving and/or case studies [PRESENCIAL][Guided or supervised work] | 2 |
Unit 10 (de 14): CARBOXYLIC ACIDS. Nomenclature. Bond and structure. Physical properties. Spectroscopic features of carboxylic acids. Acidity.Dicarboxylic acids. Carbonic acid. Origin and synthesis. Reactivity. Esterification: mechanism. Intramolecular ester formation: lactones. Decarboxylation of malonic acid and related compounds. | |
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Activities | Hours |
Class Attendance (theory) [PRESENCIAL][Lectures] | 2 |
Problem solving and/or case studies [PRESENCIAL][Guided or supervised work] | 1 |
Unit 11 (de 14): CARBOXYLIC ACID DERIVATIVES. NUCLEOPHILIC SUBSTITUION ON ACYL. Clasification. Structure and physical properties. Spectroscopic features. Reactivity (nucleophilic substitution): hydrolysis, alcoholysis, aminolysis, reduction. Reaction with organometallic compounds. Synthesis. | |
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Activities | Hours |
Class Attendance (theory) [PRESENCIAL][Lectures] | 2 |
Problem solving and/or case studies [PRESENCIAL][Guided or supervised work] | 2 |
Unit 12 (de 14): ENOLS AND ENOLATES. Acidity of ¿-hydrogen atoms. Keto-enol tautomerism. HAlogenation of aldehydes and ketones. Haloform¿s reaction. ¿-Halogenation of carboxylic acids: Hell-Volhardt-Zelinsky¿s reaction. Base-catalysed enol formation. Enolate anions, alkylation. Aldol condensation. ¿¿¿-unsaturated carbonyl compouds. 1,2- and 1,4- nucleophylic addition. Michael¿s addition and Robinson¿s annelation. | |
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Activities | Hours |
Class Attendance (theory) [PRESENCIAL][Lectures] | 3 |
Problem solving and/or case studies [PRESENCIAL][Guided or supervised work] | 2 |
Unit 13 (de 14): ENOLATES OF ESTERS AND OTHER ACID DERIVATIVES. Condensation of: Claisen, Thorpe, Knoevenagel and Perkin. Dieckman¿s condensation. Acetoacetic and Malonic synthesis. Depronotanion of carbonyl compund by lithium dialkylamidure. | |
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Activities | Hours |
Class Attendance (theory) [PRESENCIAL][Lectures] | 2 |
Problem solving and/or case studies [PRESENCIAL][Guided or supervised work] | 3 |
Global activity | |
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Activities | hours |
Author(s) | Title | Book/Journal | Citv | Publishing house | ISBN | Year | Description | Link | Catálogo biblioteca |
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Bruice, P. Y. | Organic Chemistry | Prentice Hall | 1998 | ||||||
Carey, F.A. | Química Orgánica | McGraw Hill | |||||||
Clayden, J.; Greeves, N.; Warren, S. | Organic Chemistry | Oxford University Press | 2012 | www.oxfordtextbooks.co.uk/orc/clayden2e | |||||
Enrique Díez-Barra y Sonia Merino Guijarro | Química Orgánica General en Problemas | Libro | Cuenca | Ediciones Castilla-La Mancha | 978-84-9044-41 | 2020 | |||
García Calvo-Flores, F. y Doblado Jiménez, J. A., | Problemas resueltos de Química Orgánica | Thomson | |||||||
Maria Valeria D'Auria | Guía razonada para resolver problemas de química orgánica. métodos, estrategias y explicaciones | Libro | LoghìA | 8895122453 | 2018 | ||||
McMurry, J. | Química Orgánica | Thomson | |||||||
Meislich, H.; Nechamkin, H.; Sharefkin, J. y Hademenos G., | Química Orgánica (1806 problemas resueltos) | McGraw Hill | |||||||
Morrison, R. T. y Boyd, R. N., | Química Orgánica | Addison-Wesley | |||||||
Quiñoa, E. | Nomenclatura y representación de los compuestos orgánicos: una guía de estudio y autoevaluación | McGraw Hill | |||||||
Riguera, R. y Quiñoa, E. | Cuestiones y Ejercicios de Química Orgánica | McGraw Hill | |||||||
Solomons, T. W. G. | Química Orgánica | Wiley, New York, | |||||||
Vollhardt, K. P. | Química Orgánica | Editorial Omega, Barcelona | |||||||
Wade, L.G. | Química Orgánica | Prentice-Hall |