1. General information
Course:
BIOLOGY
Code:
57303
Type:
BASIC
ECTS credits:
6
Degree:
409 - CHEMISTRY
Academic year:
2022-23
Center:
1 - FACULTY OF SCIENCE AND CHEMICAL TECHNOLOGY
Group(s):
20
23
Year:
1
Duration:
First semester
Main language:
Spanish
Second language:
English
Use of additional languages:
Occasionally some simple text or in the slides of the master classes
English Friendly:
Y
Web site:
Bilingual:
N
Lecturer:
DAVID AGUSTIN LEON NAVARRO
- Group(s):
20
23
Building/Office
Department
Phone number
Email
Office hours
Facultad de Ciencias y Tecnologías Químicas. Lab Bioquímica. Ciudad Real
QUÍMICA INORG., ORG., Y BIOQ.
926052114
davidagustin.leon@uclm.es
Monday and Friday from 1:00 p.m. to 2:00 p.m.
Monday from 4:00 p.m. to 8:00 p.m.
2. Pre-Requisites
It is recommended to have general knowledge of Biology and Chemistry.
3. Justification in the curriculum, relation to other subjects and to the profession
The subject Biology belongs to the basic training module of the Degree in Chemistry. It is located in the first year of the degree and is the first to be taught in the field of Biological Sciences, so students are able to successfully take subsequent subjects such as Biochemistry, belonging to module 3 of the Degree. With this subject, the Chemistry student takes a tour of the different levels of structural and functional organization of the cell. The fundamental principles of molecular and cellular biology, energy transformation and cell signaling are studied, all of them treated at a basic level. The teaching staff in charge of the subject is assigned to the Biochemistry area of ¿¿the Department of Inorganic, Organic and Biochemistry Chemistry of the UCLM Faculty of Chemistry, they have extensive experience in teaching and research tasks related to the contents of this discipline.
4. Degree competences achieved in this course
| Course competences | |
|---|---|
| Code | Description |
| CB01 | Prove that they have acquired and understood knowledge in a subject area that derives from general secondary education and is appropriate to a level based on advanced course books, and includes updated and cutting-edge aspects of their field of knowledge. |
| CB03 | Be able to gather and process relevant information (usually within their subject area) to give opinions, including reflections on relevant social, scientific or ethical issues. |
| E03 | Handle chemicals safely and with respect to the environment |
| E12 | Understand the chemistry of the main biological processes |
| G05 | Acquire and adapt new knowledge and techniques of any scientific-technical discipline with incidence in the chemical field |
| T02 | Domain of Information and Communication Technologies (ICT) |
| T03 | Proper oral and written communication |
| T04 | Ethical commitment and professional ethics |
5. Objectives or Learning Outcomes
| Course learning outcomes | |
|---|---|
| Description | |
| Being able to predict the thermodynamically favorable sense of a process in biological systems. | |
| Understand the importance of coupled processes in living things. | |
| Know how cell membranes are structurally and functionally organized. | |
| Know how to describe the structure and functions of cellular organelles and cytoskeleton. | |
| Know how to describe the organization of genetic material in prokaryotic and eukaryotic cells. | |
| Know how to describe the sequence of events that takes place in cell signaling. | |
| Know how to explain the influence that water exerts, due to its properties, on biomolecules. | |
| Know how to explain the control points of the cell cycle and the consequences of escaping to these controls. | |
| Know how to identify the structure and function of biological molecules. | |
| Know how to identify the stages of the eukaryotic cell cycle and describe its main processes. | |
| Know how to recognize different types of signaling molecules. | |
| Being able to compare the general characteristics of prokaryotic and eukaryotic cells and contrast plant and animal cells. | |
| Analyze the central role of ATP in the global energy metabolism of the cell. | |
| Know the strategies used in the acquisition of energy: photosynthesis, chemosynthesis, breathing. | |
| Know how to explain the control points of the cell cycle and the consequences of escaping to these controls. | |
| Additional outcomes | |
| Not established. |
6. Units / Contents
-
Unit 1: Introduction to cells. Cell types: prokaryotic and eukaryotic. General structure of a bacterium. Eukaryotic animal and plant cell.
-
Unit 2: The chemical bases of life. Chemical bonds. Biomolecules: water, carbohydrates, lipids, proteins and nucleic acids.
-
Unit 3: Use of energy by cells. Definition and types of energy. Laws of thermodynamics. Free energy. Conveyors. Enzymes activated and coupled reactions.
-
Unit 4: The flow of genetic information. The structure of eukaryotic genes. Packaging of the eukaryotic genome. DNA replication. Transcription: RNA synthesis. Translation: protein synthesis.
-
Unit 5: The plasma membrane. Structure of the plasma membrane. Plasma membrane differentiations. Small molecule transport. Vesicle-mediated transport.
-
Unit 6: Endomembrane system. Overview. Endoplasmic reticulum: types. Functions of the rough endoplasmic reticulum. Glycosylation in the rough endoplasmic reticulum. Verification of correct folding. Membrane biosynthesis in the endoplasmic reticulum. Transportation to the Golgi complex. Golgi complex. Lysosomes.Differentiations of the plasma membrane. Small molecule transport. Vesicle-mediated transport.
-
Unit 7: Structure and function of the mitochondria. Organization and function of the mitochondria. Importation of proteins into the mitochondria. Importation of lipids into the mitochondria. Transport across the inner mitochondrial membrane. Cellular respiration.
-
Unit 8: Structure and function of the chloroplast. Organization and function of the chloroplast. Importation of proteins to the chloroplast. Photosynthesis.
-
Unit 9: Cell nucleus. Nuclear envelope. Transport through the nuclear envelope. Chromatin Nucleolus
-
Unit 10: Cytoskeleton Overview. Microtubules. Microtubule organization centers. Microtubule functions. Cilia and flagella. Intermediate filaments: structure and function. Microfilaments. Motor proteins. Role of microfilaments in muscle contractility, in cytokinesis and in cellular locomotion.
-
Unit 11: Cell signaling. General principles. Receptors coupled to protein G. Receptors coupled to ion channels. Enzyme-coupled receptors.
-
Unit 12: Cell cycle. Phases of the cell cycle. Cell cycle control. Cyclin-dependent protein kinases and anaphase promoter complex. Start control point. G2 / M checkpoint. Transition from metaphase to anaphase.
7. Activities, Units/Modules and Methodology
| Training Activity | Methodology | Related Competences (only degrees before RD 822/2021) | ECTS | Hours | As | Com | Description | |
| Class Attendance (theory) [ON-SITE] | Lectures | CB01 E12 G05 | 1.16 | 29 | N | N | They have a duration of 55 minutes. PowerPoint presentations and student mobile terminals are used as audience response systems. | |
| Workshops or seminars [ON-SITE] | Combination of methods | CB01 CB03 E12 G05 T02 T03 | 0.44 | 11 | Y | N | Different types of activities are proposed in the seminars, including: activities based on just-in-time learning methodology, observation of electron microscopy micrographs, problem solving, information search and study of three-dimensional structures of biomolecules and macromolecules. | |
| Laboratory practice or sessions [ON-SITE] | Practical or hands-on activities | CB03 E03 G05 T04 | 0.48 | 12 | Y | Y | The practices will be developed in the laboratory and through them different practical aspects related to the subject will be covered. This activity is mandatory. If a student does not carry out the practices in due course, the activity will not be able to be recovered later and the subject cannot be passed. | |
| Progress test [ON-SITE] | Assessment tests | CB01 E12 G05 | 0.04 | 1 | Y | N | First partial test that allows evaluating the theoretical contents covered up to that moment. It takes place coinciding with the equator of the subject. The test takes place during class time and consists of multiple choice questions. | |
| Study and Exam Preparation [OFF-SITE] | Self-study | CB01 E12 G05 | 3.6 | 90 | N | N | Preparation of seminars and study of progress tests. | |
| Progress test [ON-SITE] | Assessment tests | CB01 E12 G05 | 0.04 | 1 | Y | N | Second progress test that takes place during the last days of theory class. Students are examined for the theoretical contents studied after the first theoretical progress test. The test takes place during class time and consists of multiple choice questions. | |
| Progress test [ON-SITE] | Assessment tests | CB01 CB03 G05 | 0.04 | 1 | Y | N | Evaluation of the practical contents by means of a theoretical test. | |
| Group tutoring sessions [ON-SITE] | Group tutoring sessions | T03 | 0.12 | 3 | N | N | Discussion and resolution of concepts and doubts. They take place a few days before the theory and practical progress tests. If less than 1 hour is needed to clarify all doubts, the rest of the time is used in class attendance (theory). They will be notified well in advance. | |
| Final test [ON-SITE] | Assessment tests | CB01 CB03 E12 G05 T03 | 0.08 | 2 | Y | N | Integrative final test that covers all the theoretical contents covered during the course. The final test includes short answer questions. The final test coincides with the ordinary call for the subject. | |
| Total: | 6 | 150 | ||||||
| Total credits of in-class work: 2.4 | Total class time hours: 60 | |||||||
| Total credits of out of class work: 3.6 | Total hours of out of class work: 90 | |||||||
As: Assessable training activity Com: Training activity of compulsory overcoming (It will be essential to overcome both continuous and non-continuous assessment).
8. Evaluation criteria and Grading System
| Evaluation System | Continuous assessment | Non-continuous evaluation * | Description |
| Progress Tests | 12.00% | 0.00% | The evaluation of laboratory practices will be based on a theoretical exam that will take place at the end of laboratory practices period. This test will include short and multiple choice questions. The qualification obtained in the 2021-22 academic could be maintained as long as it has been approved in such course. However, the student with the passed test can repeat it if he wishes |
| Progress Tests | 20.00% | 0.00% | Second theoretical progress test |
| Final test | 0.00% | 100.00% | The student will examine the theoretical and practical contents and the activities carried out during the seminars |
| Final test | 33.00% | 0.00% | Integrative test that covers all the theoretical contents covered during the course. |
| Assessment of problem solving and/or case studies | 15.00% | 0.00% | The evaluation of the seminars will be based on the results obtained in the different seminars. |
| Progress Tests | 20.00% | 0.00% | First theoretical progress test |
| Total: | 100.00% | 100.00% |
According to art. 4 of the UCLM Student Evaluation Regulations, it must be provided to students who cannot regularly attend face-to-face training activities the passing of the subject, having the right (art. 12.2) to be globally graded, in 2 annual calls per subject , an ordinary and an extraordinary one (evaluating 100% of the competences).
Evaluation criteria for the final exam:
-
Continuous assessment:o pass the subject it is necessary for the student to meet the following conditions:
a) have completed the practices.
b) have obtained a grade equal to or greater than 5 when adding the weighted grades of the different activities carried out during the course. -
Non-continuous evaluation:To pass the subject, it is necessary for the student to meet the following conditions:
a) have completed the practices.
b) have obtained a grade equal to or greater than 5 in the final test.
Specifications for the resit/retake exam:
In the resit / retake exam, the qualifications obtained in the seminars and in the practical exam are kept as long as they have been previously approved. Theoretical progress test scores are not preserved. The student therefore examines all the theoretical contents shown during the course.
The resit /retake exam allows to recover the activities of seminars and test of progress of practices if these were not passed previously.
As a summary, the value of the extraordinary call will be:
a) 73% if the student examines the theoretical contents.
b) 85% if the student takes the theoretical content and the practical progress test
c) 100% if the student examines the theoretical contents, the practical progress test and the seminars.
To pass the subject, it is necessary for the student to meet the following conditions:
a) have completed the practices.
b) When adding the qualifications, weighted according to their value, of the different activities carried out during the course, the final result must be equal to or greater tha
The resit /retake exam allows to recover the activities of seminars and test of progress of practices if these were not passed previously.
As a summary, the value of the extraordinary call will be:
a) 73% if the student examines the theoretical contents.
b) 85% if the student takes the theoretical content and the practical progress test
c) 100% if the student examines the theoretical contents, the practical progress test and the seminars.
To pass the subject, it is necessary for the student to meet the following conditions:
a) have completed the practices.
b) When adding the qualifications, weighted according to their value, of the different activities carried out during the course, the final result must be equal to or greater tha
Specifications for the second resit / retake exam:
Evaluation criteria not defined
9. Assignments, course calendar and important dates
| Not related to the syllabus/contents | |
|---|---|
| Hours | hours |
| Workshops or seminars [PRESENCIAL][Combination of methods] | 11 |
| Laboratory practice or sessions [PRESENCIAL][Practical or hands-on activities] | 12 |
| Progress test [PRESENCIAL][Assessment tests] | 1 |
| Study and Exam Preparation [AUTÓNOMA][Self-study] | 1 |
| Study and Exam Preparation [AUTÓNOMA][Self-study] | 90 |
| Study and Exam Preparation [AUTÓNOMA][Self-study] | 1 |
| Progress test [PRESENCIAL][Assessment tests] | 3 |
| Final test [PRESENCIAL][Assessment tests] | 2 |
| Unit 1 (de 12): Introduction to cells. Cell types: prokaryotic and eukaryotic. General structure of a bacterium. Eukaryotic animal and plant cell. | |
|---|---|
| Activities | Hours |
| Class Attendance (theory) [PRESENCIAL][Lectures] | 2 |
| Unit 2 (de 12): The chemical bases of life. Chemical bonds. Biomolecules: water, carbohydrates, lipids, proteins and nucleic acids. | |
|---|---|
| Activities | Hours |
| Class Attendance (theory) [PRESENCIAL][Lectures] | 3 |
| Unit 3 (de 12): Use of energy by cells. Definition and types of energy. Laws of thermodynamics. Free energy. Conveyors. Enzymes activated and coupled reactions. | |
|---|---|
| Activities | Hours |
| Class Attendance (theory) [PRESENCIAL][Lectures] | 3 |
| Unit 4 (de 12): The flow of genetic information. The structure of eukaryotic genes. Packaging of the eukaryotic genome. DNA replication. Transcription: RNA synthesis. Translation: protein synthesis. | |
|---|---|
| Activities | Hours |
| Class Attendance (theory) [PRESENCIAL][Lectures] | 4 |
| Unit 5 (de 12): The plasma membrane. Structure of the plasma membrane. Plasma membrane differentiations. Small molecule transport. Vesicle-mediated transport. | |
|---|---|
| Activities | Hours |
| Class Attendance (theory) [PRESENCIAL][Lectures] | 3 |
| Unit 6 (de 12): Endomembrane system. Overview. Endoplasmic reticulum: types. Functions of the rough endoplasmic reticulum. Glycosylation in the rough endoplasmic reticulum. Verification of correct folding. Membrane biosynthesis in the endoplasmic reticulum. Transportation to the Golgi complex. Golgi complex. Lysosomes.Differentiations of the plasma membrane. Small molecule transport. Vesicle-mediated transport. | |
|---|---|
| Activities | Hours |
| Class Attendance (theory) [PRESENCIAL][Lectures] | 2 |
| Unit 7 (de 12): Structure and function of the mitochondria. Organization and function of the mitochondria. Importation of proteins into the mitochondria. Importation of lipids into the mitochondria. Transport across the inner mitochondrial membrane. Cellular respiration. | |
|---|---|
| Activities | Hours |
| Class Attendance (theory) [PRESENCIAL][Lectures] | 2 |
| Unit 8 (de 12): Structure and function of the chloroplast. Organization and function of the chloroplast. Importation of proteins to the chloroplast. Photosynthesis. | |
|---|---|
| Activities | Hours |
| Class Attendance (theory) [PRESENCIAL][Lectures] | 2 |
| Unit 9 (de 12): Cell nucleus. Nuclear envelope. Transport through the nuclear envelope. Chromatin Nucleolus | |
|---|---|
| Activities | Hours |
| Class Attendance (theory) [PRESENCIAL][Lectures] | 2 |
| Unit 10 (de 12): Cytoskeleton Overview. Microtubules. Microtubule organization centers. Microtubule functions. Cilia and flagella. Intermediate filaments: structure and function. Microfilaments. Motor proteins. Role of microfilaments in muscle contractility, in cytokinesis and in cellular locomotion. | |
|---|---|
| Activities | Hours |
| Class Attendance (theory) [PRESENCIAL][Lectures] | 2 |
| Unit 11 (de 12): Cell signaling. General principles. Receptors coupled to protein G. Receptors coupled to ion channels. Enzyme-coupled receptors. | |
|---|---|
| Activities | Hours |
| Class Attendance (theory) [PRESENCIAL][Lectures] | 2 |
| Unit 12 (de 12): Cell cycle. Phases of the cell cycle. Cell cycle control. Cyclin-dependent protein kinases and anaphase promoter complex. Start control point. G2 / M checkpoint. Transition from metaphase to anaphase. | |
|---|---|
| Activities | Hours |
| Class Attendance (theory) [PRESENCIAL][Lectures] | 2 |
| Progress test [PRESENCIAL][Assessment tests] | 1 |
| Global activity | |
|---|---|
| Activities | hours |
10. Bibliography and Sources