Guías Docentes Electrónicas
1. General information
Course:
ORGANIC CHEMISTRY II
Code:
14318
Type:
CORE COURSE
ECTS credits:
6
Degree:
376 - UNDERGRADUATE DEGREE PROGRAMME IN PHARMACY
Academic year:
2022-23
Center:
14 - FACULTY OF PHARMACY
Group(s):
10 
Year:
2
Duration:
First semester
Main language:
Spanish
Second language:
English
Use of additional languages:
English Friendly:
Y
Web site:
Bilingual:
N
Lecturer: JOAQUIN CALIXTO GARCIA MARTINEZ - Group(s): 10 
Building/Office
Department
Phone number
Email
Office hours
Facultad de Farmacia
QUÍMICA INORG., ORG., Y BIOQ.
+34926053224
joaquinc.garcia@uclm.es

Lecturer: ANTONIO MANUEL RODRÍGUEZ GARCÍA - Group(s): 10 
Building/Office
Department
Phone number
Email
Office hours
Facultad de Farmacia
QUÍMICA INORG., ORG., Y BIOQ.
AntonioM.Rodriguez@uclm.es

2. Pre-Requisites

No prerequisites are established for this subject although it is recommended that the student has previously passed Organic Chemistry I.

3. Justification in the curriculum, relation to other subjects and to the profession

As experts in medicines and their use for therapeutic purposes in humans, the future pharmacist has to know the structure and chemical properties of the main groups of natural and heterocyclic products, since many drugs biomimic the structure and functions of many of them. This subject together with Organic Chemistry I forms the basis for Pharmaceutical Chemistry I and Pharmaceutical Chemistry II. In addition, the concepts of characterization and structural determination using spectroscopic techniques, mainly nuclear magnetic resonance (NMR) and infrared spectroscopy (IR), are introduced.


4. Degree competences achieved in this course
Course competences
Code Description
B01 Proficiency in a second foreign language at level B1 of the Common European Framework of Reference for Languages.
B02 Knowledge of Information and Communication Technologies (ICT).
B03 A correct oral and written communication
B04 Ethical commitment and professional deontology.
B05 Ability to develop those learning skills necessary to undertake further studies.
EQ01 Identify, design, prepare, analyse and produce active principles, drugs and other materials and products of sanitary interest. 
EQ02 Adequately choose the techniques and methodologies for the evaluation, design and application of chemical reagents, laboratory methodologies and analytical techniques.
EQ03 Complete standard laboratory processes including the employment of scientific equipment related to synthesis and analysis.
EQ04 Evaluate risks/hazards associated to the use of chemical substances and lab processes.
EQ08 Know and understand the chemical nature and behavior of functional groups in organic molecules.
EQ11 Know and apply the main structural determination techniques, including spectroscopy.
G01 Identify, design, obtain, analyze, control and produce drugs and medicines, as well as other products and raw materials of sanitary interest for human or veterinary use.
G02 Evaluate the therapeutic and toxic effects of substances with pharmacological activity.
G03 Know how to apply the scientific method and acquire skills in the handling of legislation, sources of information, bibliography, elaboration of protocols and other aspects considered necessary for the design and critical evaluation of preclinical and clinical trials.
G04 Design, prepare, supply and dispense medicines and other products of health interest.
G05 Provide therapeutic advice in pharmacotherapy and dietotherapy, as well as in the nutritional and food field in the establishments where they provide services.
G06 Promote the rational use of medicines and medical devices, as well as to acquire basic knowledge in clinical management, health economics and the efficient use of health resources.
G07 Identify, evaluate and assess problems related to drugs and medicines, as well as participate in pharmacovigilance activities.
G08 Conducting clinical and social pharmacy activities, following the pharmaceutical care cycle.
G09 Intervene in health promotion and disease prevention activities at the individual, family and community levels, with an integral and multi-professional vision of the health-disease process.
G10 Design, apply and evaluate clinical reagents, methods and analytical techniques, knowing the basic principles of clinical analysis and the characteristics and contents of laboratory diagnostic reports.
G11 Evaluate the toxicological effects of substances and design and apply appropriate tests and trials.
G12 Develop hygienic-sanitary analyses, especially those related to food and environment.
G13 Develop communication and information skills, both oral and written, to deal with patients and users of the centre where they carry out their professional activity. Promote the capacity to work and collaborate with multidisciplinary teams and those related to other health professionals.
G14 Know the ethical and deontological principles according to the legislative, regulatory and administrative provisions governing professional practice, understanding the ethical implications of health in a changing social context.
G15 Recognise own limitations and the need to maintain and update professional competence, with particular emphasis on self-learning of new knowledge based on scientific evidence.
T01 Critical thinking skills based on the application of the scientific method
T02 Ability to manage quality scientific information, bibliography, specialized databases and resources accessible through the Internet.
T03 Handling of basic and specific software for the treatment of information and experimental results.
T04 Motivation for quality, safety at work and awareness of environmental issues, with knowledge of the internationally recognised systems for the correct management of these aspects.
T05 Organizational, planning and implementation skills.
T06 Ability to address human resources decision-making and management.
T07 Ability to work as a team and, where appropriate, exercise leadership functions, encouraging entrepreneurship.
T08 Develop interpersonal skills and the ability to function in an international and multicultural context.
5. Objectives or Learning Outcomes
Course learning outcomes
Description
Preparation of reports, summaries and presentations on bibliographic or experimental works, either individually or in teams, applying the capacity for criticism and self-criticism.
Ability to design simple organic compound synthesis from certain starting products and involving more than one reaction.
Characterization and identification of functional groups in organic compounds.
Ability to apply the knowledge acquired in laboratory practice and in solving problems and issues related to organic compounds.
Ability to name organic compounds according to IUPAC standards and represent their structure from the systematic name.
Correlate the structure of organic compounds with their physical properties, reactivity and stability.
To develop the necessary laboratory processes for the transformation, separation, isolation and purification of organic compounds, estimating the possible associated risks.
Structural determination of organic compounds from their chemical properties and chemical analysis data.
Recognize the three-dimensional structure of organic compounds and its implications.
Additional outcomes
Not established.
6. Units / Contents
  • Unit 1: Aromatic Electrophic Substitution (ArES)
    • Unit 1.1: Reaction ArES over benzene
    • Unit 1.2: Mechanism of ArSE
    • Unit 1.3: Influence of substituyent in ArES
    • Unit 1.4: Synthesis of substituteb benzenes
    • Unit 1.5: polyaromatic compounds
  • Unit 2: Structural determination of Organic Compounds
    • Unit 2.1: Infrared spectroscopy
    • Unit 2.2: Nuclear Magnetic Resonance Spectroscopy
  • Unit 3: Heterocyclic compounds
    • Unit 3.1: Amromaticity of heterocyclic compounds
    • Unit 3.2: 6-members ring heterocycles
    • Unit 3.3: 5-members ring heterocycles
    • Unit 3.4: synthesis of heterocycles
  • Unit 4: Aminoacid, peptides and proteins
    • Unit 4.1: Structure of aminoacid and peptides
    • Unit 4.2: acid and basic properties
    • Unit 4.3: synthesis of aminoacid
    • Unit 4.4: reactivity of aminoacid
    • Unit 4.5: peptides
    • Unit 4.6: synthesis of peptides
  • Unit 5: Carbohydrates and nucleic acids
    • Unit 5.1: Classification of carbohydrates
    • Unit 5.2: cyclic forms of carbohydrates
    • Unit 5.3: mutarrotation
    • Unit 5.4: Mutarrotation
    • Unit 5.5: Glicosides, disaccharides and polysaccharides
    • Unit 5.6: Reactivity of monosaccharides
    • Unit 5.7: Nucleic acid
  • Unit 6: Laboratory Practices
    • Unit 6.1: Synthesis con Cinnamic Acid. Use of Spectroscopic techniques
    • Unit 6.2: ArES. Synthesis of Martius Yellow
    • Unit 6.3: Synthesis of Knorr.
    • Unit 6.4: Chemistry of Milk. Proteins and Carbohydrates
7. Activities, Units/Modules and Methodology
Training Activity Methodology Related Competences (only degrees before RD 822/2021) ECTS Hours As Com Description
Class Attendance (theory) [ON-SITE] Combination of methods B01 B02 B03 B04 B05 EQ01 EQ02 EQ08 EQ11 G01 G02 G03 G04 G05 G06 G07 G08 G09 G10 G11 G12 G13 G14 G15 T01 T02 T03 T04 T05 T06 T07 T08 0.92 23 Y N
Laboratory practice or sessions [ON-SITE] B01 B02 B03 B04 B05 EQ02 EQ03 EQ04 EQ08 EQ11 G01 G02 G03 G04 G05 G06 G07 G08 G09 G10 G11 G12 G13 G14 G15 T01 T02 T03 T04 T05 T06 T07 T08 0.8 20 Y Y
Workshops or seminars [ON-SITE] Combination of methods B01 B02 B03 B04 B05 EQ01 EQ02 EQ08 EQ11 G01 G02 G03 G04 G05 G06 G07 G08 G09 G10 G11 G12 G13 G14 G15 T01 T02 T03 T04 T05 T06 T07 T08 0.52 13 Y N
Study and Exam Preparation [OFF-SITE] Problem solving and exercises B01 B02 B03 B04 B05 EQ01 EQ02 EQ03 EQ04 EQ08 EQ11 G01 G02 G03 G04 G05 G06 G07 G08 G09 G10 G11 G12 G13 G14 G15 T01 T02 T03 T04 T05 T06 T07 T08 2.07 51.75 Y N
Study and Exam Preparation [OFF-SITE] Assessment tests B01 B02 B03 B04 B05 EQ01 EQ02 EQ03 EQ04 EQ08 EQ11 G01 G02 G03 G04 G05 G06 G07 G08 G09 G10 G11 G12 G13 G14 G15 T01 T02 T03 T04 T05 T06 T07 T08 1.53 38.25 Y N
Mid-term test [ON-SITE] Combination of methods B01 B02 B03 B04 B05 EQ01 EQ02 EQ03 EQ04 EQ08 EQ11 G01 G02 G03 G04 G05 G06 G07 G08 G09 G10 G11 G12 G13 G14 G15 T01 T02 T03 T04 T05 T06 T07 T08 0.16 4 Y N
Total: 6 150
Total credits of in-class work: 2.4 Total class time hours: 60
Total credits of out of class work: 3.6 Total hours of out of class work: 90

As: Assessable training activity
Com: Training activity of compulsory overcoming (It will be essential to overcome both continuous and non-continuous assessment).

8. Evaluation criteria and Grading System
Evaluation System Continuous assessment Non-continuous evaluation * Description
Test 70.00% 70.00%
Laboratory sessions 20.00% 20.00%
Assessment of active participation 10.00% 10.00%
Total: 100.00% 100.00%  
According to art. 4 of the UCLM Student Evaluation Regulations, it must be provided to students who cannot regularly attend face-to-face training activities the passing of the subject, having the right (art. 12.2) to be globally graded, in 2 annual calls per subject , an ordinary and an extraordinary one (evaluating 100% of the competences).

Evaluation criteria for the final exam:
  • Continuous assessment:
    Evaluation criteria not defined
  • Non-continuous evaluation:
    Evaluation criteria not defined

Specifications for the resit/retake exam:
Evaluation criteria not defined
Specifications for the second resit / retake exam:
Evaluation criteria not defined
9. Assignments, course calendar and important dates
Not related to the syllabus/contents
Hours hours
Class Attendance (theory) [PRESENCIAL][Combination of methods] 23
Laboratory practice or sessions [PRESENCIAL][] 20
Workshops or seminars [PRESENCIAL][Combination of methods] 13
Study and Exam Preparation [AUTÓNOMA][Problem solving and exercises] 51.75
Study and Exam Preparation [AUTÓNOMA][Assessment tests] 38.25
Mid-term test [PRESENCIAL][Combination of methods] 4

Global activity
Activities hours
10. Bibliography and Sources
Author(s) Title Book/Journal Citv Publishing house ISBN Year Description Link Catálogo biblioteca
La editorial Pearson tiene varios libros de Química Orgánica Acceso on line libre para alumnos http://www.conten.es/ib/NPortada?CodPortada=1000188  
La editorial Digitalia tiene varios libros de Química Orgánica Acceso on line libre para alumnos http://www.digitaliapublishing.com/  
Carey, Francis A. Organic chemistry McGraw-Hill 0-07-009831-X 1987 Ficha de la biblioteca
Carey, Francis A. Química orgánica McGraw Hill 970-10-5610-8 2006 Ficha de la biblioteca
Carey, Francis A. Organic chemistry McGraw-Hill 0-07-115148-6 2003 Ficha de la biblioteca
Carey, Francis A. Química orgánica McGraw-Hill 84-481-2426-X 1999 Ficha de la biblioteca
Hesse, M., Meier, H., Zeeh, B. Métodos Espectroscópicos en Química Orgánica Ed. Síntesis 9788477385226 2005  
VOLLHARDT, K. Peter C. Organic Chemistry W. H. Freeman and Company 0-7167-1786-7 1987 Ficha de la biblioteca
VOLLHARDT, K. Peter C. Química orgánica Omega 84-282-1006-3 1995 Ficha de la biblioteca
Vollhardt, K. Peter C. Química Orgánica Omega 84-282-0882-4 1990 Ficha de la biblioteca
Vollhardt, K. Peter C. Química orgánica Omega 84-282-0882-4 1994 Ficha de la biblioteca
Vollhardt, K. Peter C. Química orgánica : estructura y función Omega 84-282-1172-8 2000 Ficha de la biblioteca
Vollhardt, K. Peter C. Química orgánica : estructura y función Omega 978-84-282-1431-5 2007 Ficha de la biblioteca
Vollhardt, K. Peter C. Organic chemistry W. H. Freeman and Company 0-7167-2010-8 1994 Ficha de la biblioteca
Vollhardt, K. Peter C. Organic chemistry : structure and function W. H. Freeman and Company 0-7167-2721-8 1998 Ficha de la biblioteca
Vollhardt, K. Peter C. Química orgánica Omega 84-282-1006-3 1995 Ficha de la biblioteca
Yurkanis, P. Química Orgánica Pearson 9789702607915 2007  



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