Guías Docentes Electrónicas
1. General information
ECTS credits:
Academic year:
Main language:
Second language:
Use of additional languages:
English Friendly:
Web site:
Lecturer: ANA MARIA BORREGUERO SIMON - Group(s): 21 
Phone number
Office hours
Enrique Costa Novella/Despacho 12

Phone number
Office hours
Enrique Costa Novella/Despacho 14
Tuesday, Wednesday and Thursday from 12:00 to 13:00

2. Pre-Requisites
Not established
3. Justification in the curriculum, relation to other subjects and to the profession

Subject belonging to Module 3 (Specific technology in Industrial chemistry). Biochemical engineering is concerned with the study, planning, design and operation of industrial chemical processes in which the transformation stage of raw materials is carried out through biochemical reactions (using different microorganisms) or enzymatic reactions. This type of process is very common in the chemical industry, food and beverage industry, drug production or environmental waste treatment.

4. Degree competences achieved in this course
Course competences
Code Description
CB05 Have developed the necessary learning abilities to carry on studying autonomously
E19 Knowledge about material and energy balances, biotechnology, material transfer, separation operations, chemical reaction engineering, reactor design, and recovery and transformation of raw materials and energy resources.
E21 Capacity for the design and management of applied experimentation procedures, especially for the determination of thermodynamic and transport properties, and modeling of phenomena and systems in the field of chemical engineering, systems with fluid flow, heat transfer, mass transference, kinetics of chemical reactions and reactors.
G04 Knowledge for the realization of measurements, calculations, valuations, appraisals, surveys, studies, reports, work plans and other analogous works.
G16 Capacity for critical thinking and decision making
G17 Synthesis capacity
G18 Capacity for teamwork
G19 Ability to analyze and solve problems
G20 Ability to learn and work autonomously
G21 Ability to apply theoretical knowledge to practice
G22 Creativity and initiative
5. Objectives or Learning Outcomes
Course learning outcomes
To have knowledge to adequately control the functioning of biotechnological processes.
To have knowledge to design operations of conditioning of substrates and processing of products in biochemical processes.
To have knowledge to design enzymatic reactors.
To have knowledge to design industrial fermentors.
To know how to select among several alternatives in a biotechnological process.
Additional outcomes
Not established.
6. Units / Contents
  • Unit 1: Biochemical reactors
  • Unit 2: Enzyme reactors
  • Unit 3: Agitation and mixing
  • Unit 4: Aeration of Fermenters
  • Unit 5: Drying solids
  • Unit 6: Lyophilization
  • Unit 7: Esterification of Culture Media
  • Unit 8: Biotechnology processes of industrial interest
7. Activities, Units/Modules and Methodology
Training Activity Methodology Related Competences ECTS Hours As Com Description
Class Attendance (theory) [ON-SITE] Lectures CB05 E19 E21 G04 G16 G17 G18 G20 G22 1.4 35 N N
Mid-term test [ON-SITE] Assessment tests CB05 E19 E21 G04 G16 G17 G18 G19 G20 G22 0.1 2.5 Y Y
Laboratory practice or sessions [ON-SITE] Practical or hands-on activities CB05 E19 E21 G04 G16 G17 G18 G19 G20 G22 0.2 5 Y Y
Problem solving and/or case studies [ON-SITE] Project/Problem Based Learning (PBL) CB05 E19 E21 G04 G16 G17 G18 G19 G20 G21 G22 0.6 15 Y Y
Group tutoring sessions [ON-SITE] Group tutoring sessions CB05 E19 E21 G04 G19 G21 0.1 2.5 N N
Study and Exam Preparation [OFF-SITE] Self-study CB05 E19 E21 G04 G16 G17 G18 G19 G20 G21 G22 3.6 90 N N
Total: 6 150
Total credits of in-class work: 2.4 Total class time hours: 60
Total credits of out of class work: 3.6 Total hours of out of class work: 90

As: Assessable training activity
Com: Training activity of compulsory overcoming (It will be essential to overcome both continuous and non-continuous assessment).

8. Evaluation criteria and Grading System
Evaluation System Continuous assessment Non-continuous evaluation * Description
Practicum and practical activities reports assessment 10.00% 10.00% The elaboration of practice memoirs in the classroom is included.
Mid-term tests 65.00% 0.00% The progress tests go into the evaluation option.
Laboratory sessions 15.00% 15.00% The realization of laboratory practices is an activity.
Assessment of problem solving and/or case studies 10.00% 10.00% Solving problems or global cases is done.
Final test 0.00% 65.00%
Total: 100.00% 100.00%  
According to art. 4 of the UCLM Student Evaluation Regulations, it must be provided to students who cannot regularly attend face-to-face training activities the passing of the subject, having the right (art. 12.2) to be globally graded, in 2 annual calls per subject , an ordinary and an extraordinary one (evaluating 100% of the competences).

Evaluation criteria for the final exam:
  • Continuous assessment:
    The criteria indicated in each of the training activities and the percentages of the evaluation system shall apply. To approve the subject in each of the sections will require a minimum of a 4.0/10 and the average must be equal to or greater than 5.0/10.
  • Non-continuous evaluation:
    Evaluation criteria not defined

Specifications for the resit/retake exam:
They follow the same criteria as in the ordinary.
Specifications for the second resit / retake exam:
The character of compulsory realization, the minimum note, and the recoverable character is maintained as in the ordinary call.
9. Assignments, course calendar and important dates
Not related to the syllabus/contents
Hours hours
Class Attendance (theory) [PRESENCIAL][Lectures] 35
Mid-term test [PRESENCIAL][Assessment tests] 2.5
Laboratory practice or sessions [PRESENCIAL][Practical or hands-on activities] 5
Problem solving and/or case studies [PRESENCIAL][Project/Problem Based Learning (PBL)] 15
Group tutoring sessions [PRESENCIAL][Group tutoring sessions] 2.5
Study and Exam Preparation [AUTÓNOMA][Self-study] 90

Global activity
Activities hours
10. Bibliography and Sources
Author(s) Title Book/Journal Citv Publishing house ISBN Year Description Link Catálogo biblioteca
AIBA, Shuichi Biochemical engineering Academic Press 0-12-045052-6 1973 Ficha de la biblioteca
ATKINSON, Bernard Biochemical engineering and biotechnology handbook Stockton Press 0-943818-02-8 1987 Ficha de la biblioteca
Atkinson, B. Reactores bioquímicos Reverté 84-291-7009-X 1986 Ficha de la biblioteca
B. Atkinson, F. Mavituna Biochemical engineering and biotechnology handbook U.K. Macmillan Publishers Ltd. 0-333-33274-1 1983  
BAILEY, James E. Biochemical engineering fundamentals McGraw-Hill 0-07-003212-2 1986 Ficha de la biblioteca
Dutta, Rajiv Fundamentals of biochemical engineering Ane Books India Springer 978-81-8052-202-4 2008 Ficha de la biblioteca
Gòdia Casablancas, Francesc; López Santín, Josep; Casas Alvero, Carlos Ingeniería bioquímica Síntesis 84-7738-611-0 1998 Ficha de la biblioteca
Katoh, S., Horiuchi, J. y Yoshida, F. Biochemical engineering: a textbook for engineers, chemists and biologists. Wiley-VCH Verlag GmbH & Co. KGaA, cop 978-3-527-33804-7 2015  
Kent, J. A.; Bommaraju, T.; Barnicki, S. D. Handbook of Industrial Chemistry and Biotechnology Springer 978-3-319-52287-6 2017  
Kirk y Othmer Enciclopedia de Tecnología Química Limusa S.A 968-18-5576-0 1998  
Lee, James M. Biochemical engineering Prentice Hall 0-13-085317-8 1992 Ficha de la biblioteca
Okafor, N. y Okeke B.C Modern Industrial Microbiology and Biotechnology CRC Press - Taylor & Francis Group 9781138550186 2017  
Quintero Ramírez, Rodolfo Ingeniería bioquímica : teoría y aplicaciones Alhambra mexicana, 968-444-017-0 1987 Ficha de la biblioteca
Ratledge, Colin; Kristiansen, Bjorn Biotecnología básica Zaragoza : Acribia, D.L 978-84-200-1133-2 2009 Ficha de la biblioteca
Scragg, A Biotecnología para Ingenieros: sistemas biológicos en procesos tecnológicos Limusa S.A 978-968-18-4708-1 2008  
Shuler, M.L Chemical Engineering Problems in Biotechnology American Institure of Chemical Engineers 0-8169-0469-3 1989  
Steudler, S., Werner, A., Cheng, J.J Solid State Fermentation: Research and Industrial Applications. Springer 3030236757, 97830302 2019  

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