Guías Docentes Electrónicas
1. General information
Course:
MOLECULAR ENDOCRINOLOGY
Code:
13331
Type:
ELECTIVE
ECTS credits:
4.5
Degree:
341 - UNDERGRADUATE DEGREE PROGRAMME IN BIOCHEMISTRY
Academic year:
2022-23
Center:
501 - FACULTY OF ENVIRONMENTAL SCIENCES AND BIOCHEMISTRY
Group(s):
40 
Year:
4
Duration:
First semester
Main language:
Spanish
Second language:
Spanish
Use of additional languages:
English Friendly:
Y
Web site:
Bilingual:
N
Lecturer: ROSARIO SERRANO VARGAS - Group(s): 40 
Building/Office
Department
Phone number
Email
Office hours
Room 28/Building 6
QUÍMICA INORG., ORG., Y BIOQ.
5484
rosario.serrano@uclm.es

2. Pre-Requisites
Not established
3. Justification in the curriculum, relation to other subjects and to the profession


The subject “Molecular endocrinology”, addresses the study of the physiologic mechanisms involved in neuroendocrine regulation of organ function. Its study is approached from an integrated point of view, including neural, immune and metabolic regulation and interaction in different physiologic and pathological conditions.

The teaching of this subject is based on previous knowledge acquired in the subjects of Signaling, control and cellular homeostasis, 2nd year and Human Physioloy, Metabolism and its regulation and Clinical biochemistry taught in the 3rd course.

From a professional point of view, the subjects provides theorical and practical knowledge of the endocrine system, general concepts of hormone production and release, cellular mechanisms of action as well as the clinical implications of each endocrine organ, that will be necesary for the development of some professional facets of a graduate in Biochemistry in his clinical and research point of view.


4. Degree competences achieved in this course
Course competences
Code Description
E01 Express themselves correctly in basic biological, physical, chemical, mathematical and computer terms.
E09 Be familiar with the different cell types (prokaryotes and eukaryotes) at the level of structure, physiology and biochemistry and be able to critically explain how their properties are adapted to their biological function.
E29 To interpret the results of the biochemical parameters of a blood and urine analysis, among others, suggesting the orientation of the possible underlying pathologies of the alterations found.
G01 To possess and understand the knowledge in the area of Biochemistry and Molecular Biology at a level that, based on advanced textbooks, also includes cutting-edge aspects of relevance in the discipline
G04 To know how to transmit information, ideas, problems and solutions in the field of Biochemistry and Molecular Biology to a specialized and non-specialized public.
T02 User-level knowledge of Information and Communication Technologies (ICT).
T03 A correct oral and written communication
T05 Organizational and planning skills
T08 Ability to work as a team and, where appropriate, exercise leadership functions, encouraging entrepreneurship
5. Objectives or Learning Outcomes
Course learning outcomes
Description
The professional profile "molecular biomedicine" includes the application of biochemistry in the health sector, so that the student receives a strong biomedical and clinical orientation and also acquires the skills to carry out a professional activity in the field of teaching and research.
Additional outcomes
Description
6. Units / Contents
  • Unit 1: Introduction to endocrine system
    • Unit 1.1: General principles of endocrine physiology
    • Unit 1.2: Assessment of endocrine function
  • Unit 2: Molecular Basis of endocrinology
    • Unit 2.1: The Hypothalamus ans Pituitary gland
    • Unit 2.2: Thyroid gland
    • Unit 2.3: Adrenal gland
    • Unit 2.4: Male and female reproductive system
    • Unit 2.5: Endocrine pancreas
    • Unit 2.6: Calcium homeostasis
  • Unit 3: Laboratory lessons
7. Activities, Units/Modules and Methodology
Training Activity Methodology Related Competences (only degrees before RD 822/2021) ECTS Hours As Com Description
Class Attendance (theory) [ON-SITE] Lectures 1.08 27 N N
Workshops or seminars [ON-SITE] Combination of methods E01 G01 G04 T03 T08 0.2 5 Y N Non-recoverable activity
Study and Exam Preparation [OFF-SITE] Self-study E09 E29 G01 T02 T05 2.7 67.5 N N
Final test [ON-SITE] Assessment tests E01 E09 E29 G01 G04 T03 0.08 2 Y Y Theorical classes. Recoverable activity in the retake exam
Laboratory practice or sessions [ON-SITE] Practical or hands-on activities E29 T05 0.4 10 Y Y Non-recoverable activity
Final test [ON-SITE] Assessment tests E09 E29 0.04 1 Y Y Practical classes. Recoverable activity in the retake exam
Total: 4.5 112.5
Total credits of in-class work: 1.8 Total class time hours: 45
Total credits of out of class work: 2.7 Total hours of out of class work: 67.5

As: Assessable training activity
Com: Training activity of compulsory overcoming (It will be essential to overcome both continuous and non-continuous assessment).

8. Evaluation criteria and Grading System
Evaluation System Continuous assessment Non-continuous evaluation * Description
Final test 80.00% 90.00% Topics evaluation
Assessment of problem solving and/or case studies 10.00% 0.00% Workshops evaluation
Laboratory sessions 10.00% 10.00% Laboratory lessons evaluation
Total: 100.00% 100.00%  
According to art. 4 of the UCLM Student Evaluation Regulations, it must be provided to students who cannot regularly attend face-to-face training activities the passing of the subject, having the right (art. 12.2) to be globally graded, in 2 annual calls per subject , an ordinary and an extraordinary one (evaluating 100% of the competences).

Evaluation criteria for the final exam:
  • Continuous assessment:
    It is compulsory to obtain a score equal to 4 or higher in the laboratory sessions (compulsory attendance + evaluation) to pass the course
    It is mandatory to obtain a score equal to 4 or higher in the final test to add all other evaluable parts (labs and seminars)
    The subject will only be considered passed if the sum of all the evaluable activities results in a grade of 5 or higher (out of 10)
    The modality assigned by default to the student will be the continuous evaluation. Any student may request the change to the modality of non-continuous evaluation (before the end of the class period) by emailing the teacher, provided that he has not completed 50% of the evaluable activities. "
  • Non-continuous evaluation:
    It is compulsory to obtain a score equal to 4 or higher in the laboratory sessions (compulsory attendance + evaluation) to pass the course
    It is mandatory to obtain a score equal to 4 or higher in the final test to add all other evaluable parts (labs)
    The subject will only be considered passed if the sum of all the evaluable activities results in a grade of 5 or higher (out of 10)

Specifications for the resit/retake exam:
The marks from the laboratory sessions and seminars are maintained until the Make-up Exam.
It is compulsory to obtain a score equal to 4 or higher in the laboratory sessions (compulsory attendance + evaluation) to pass the course
It is mandatory to obtain a score equal to 4 or higher in the final test to add all other evaluable parts (labs and seminars)
The subject will only be considered passed if the sum of all the evaluable activities results in a grade of 5 or higher (out of 10)
Specifications for the second resit / retake exam:
The mark obtained in the exam will be 100% of the final evaluation. It is mandatory to obtain a score equal to 5 or higher.
It is mandatory to have done the laboratory sessions to pass the course.
9. Assignments, course calendar and important dates
Not related to the syllabus/contents
Hours hours

Unit 1 (de 3): Introduction to endocrine system
Activities Hours
Class Attendance (theory) [PRESENCIAL][Lectures] 4
Workshops or seminars [PRESENCIAL][Combination of methods] 1
Study and Exam Preparation [AUTÓNOMA][Self-study] 5

Unit 2 (de 3): Molecular Basis of endocrinology
Activities Hours
Class Attendance (theory) [PRESENCIAL][Lectures] 24
Workshops or seminars [PRESENCIAL][Combination of methods] 4
Study and Exam Preparation [AUTÓNOMA][Self-study] 57.5
Final test [PRESENCIAL][Assessment tests] 2

Unit 3 (de 3): Laboratory lessons
Activities Hours
Laboratory practice or sessions [PRESENCIAL][Practical or hands-on activities] 10

Global activity
Activities hours
10. Bibliography and Sources
Author(s) Title Book/Journal Citv Publishing house ISBN Year Description Link Catálogo biblioteca
Antonino Jara Albarrán. Endocrinología - Diabetes y Metabolismo. 2th edition. Editorial médica panamericana 9788498352351  
David Gardner & Dolores Shoback Greenspan's Basic & Clinical Endocrinology. 9th ed. McGraw Hill 9780071622431 2011  
John Hancock. Cell signaling. 3th edition. Oxford University Press 9780199232109 2010  
John W. Baynes & Marek H. Dominiczak. Bioquímica médica 3th edition Elsevier 978-84-8086-730-6 2011 Ficha de la biblioteca
Mac E. Hadley Endocrinología. 4ª edición. Prentice Hall. 848966014X 1997  
Melmed &Polonsky &Larsen&Kronenberg. Williams Textbook of Endocrinology. 12th Edition. Saunders. 9781437736007 2011  
Patricia Molina Endocrine Physiology, Fourth Edition. McGraw Hill 780071796774 2013  



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