Not established

 

Mass spectrometry is a fundamental tool in many fields of research. It allows the identification of substances, characterization of their structures and their concentrations. It is also allowing technological development in various fields such as pharmacy and biotechnology, research in materials, energy, petrochemical, gas analysis, atmosphere and environment, nanoparticles, etc. The utility of mass spectrometry is spreading thanks to its couplings with other techniques such as GC-MS, LC-MS, ICP-MS, SPME, etc.

The basic aspects of mass spectrometry are the subject of study in the majority of Chemistry degrees. However, a deeper knowledge of the fundamentals of the technique and of the technological aspects in relation to the methods of sampling, ionization, separation and detection of ions is required. This knowledge allows the effective application of mass spectrometry in different professional and research fields.

Course competences
Code	Description
E05	Knowing the usefulness of separation techniques, analysis and structural determination, their joint application in the resolution of research problems, as well as possessing skills in the use of such techniques.
E09	Knowing the possibilities offered by new analytical methodologies in different fields of application, such as environmental analysis, pharmacological analysis, etc.
E12	Being able to plan and develop projects and experiments, as well as linking different scientific specialties (interdisciplinary character).
T01	Capacity for organization, planning and decision making.
T05	Ability to obtain bibliographic information at the research level, including Internet resources (databases, specialized scientific bibliography, social networks, etc ...), as well as carry out a selection and classification of it.

Course learning outcomes
Description
To acquire exhaustive knowledge of the separation techniques/mass spectrometry interfaces and to identify the advantages and drawbacks of each kind of interface.
To reinforce the required knowledge to interpret mass spectra in characterization problems, quantitative sample analysis and process monitoring
To be able to operate mass spectrometry equipment
To know the different techniques of sampling, ionization and separation of ions in mass spectrometry equipment.
Additional outcomes
Not established.

• Unit 1: Introduction to mass spectrometry
• Unit 2: Vacuum and high vacuum technologies
• Unit 3: Ionization methods. Volatile and low volatile substances. Electron impact, chemical ionization, ionization by field, desorption by laser, bombardment by fast atoms, desorption by plasma, secondary ions
• Unit 4: Mass analyzers Ion separation Sectors, quadrupole, Ion Trap, flight time. Ion detectors
• Unit 5: Inlet systems for different types of samples
• Unit 6: Applications of mass spectrometry. Coupling of MS with other analytical techniques. GC-MS, LC-MS, ICP-MS
• Unit 7: Experimental sessions

Training Activity	Methodology	Related Competences (only degrees before RD 822/2021)	ECTS	Hours	As	Com	R	Description *
Class Attendance (theory) [ON-SITE]	Lectures	E05 E09 E12	1	25	N	N	N
Workshops or seminars [ON-SITE]	Problem solving and exercises	E05 E09 E12	0.4	10	Y	N	N
Laboratory practice or sessions [ON-SITE]	Practical or hands-on activities	E05 E09 E12 T01 T05	0.72	18	Y	Y	N
Final test [ON-SITE]	Assessment tests	E05 E09 E12 T01 T05	0.08	2	Y	Y	Y
Study and Exam Preparation [OFF-SITE]	Self-study	E05 E09 T05	2	50	N	N	N
Other off-site activity [OFF-SITE]	Self-study	E05	0.6	15	N	N	N
Study and Exam Preparation [OFF-SITE]	Assessment tests	E05 E09 E12	0.4	10	N	N	N
Practicum and practical activities report writing or preparation [OFF-SITE]	Practical or hands-on activities	T05	0.8	20	N	N	N
Total:			6	150
Total credits of in-class work: 2.2			Total class time hours: 55
Total credits of out of class work: 3.8			Total hours of out of class work: 95

As: Assessable training activity
Com: Training activity of compulsory overcoming
R: Rescheduling training activity

	Grading System
Evaluation System	Face-to-Face	Self-Study Student	Description
Final test	40.00%	0.00%
Laboratory sessions	30.00%	0.00%	Experiments in research laboratory and report
Assessment of problem solving and/or case studies	20.00%	0.00%	Problem solving and practical cases of application in mass spectrometry.
Other methods of assessment	10.00%	0.00%	Design of an experiment to aply the fundaments of mass spectrometry
Total:	100.00%	0.00%

Not related to the syllabus/contents
Hours	hours

Author(s)	Title	Book/Journal	Citv	Publishing house	ISBN	Year	Description	Link	Catálogo biblioteca
Edmond de Hoffmann y Vicent Stroobant	Mass Spectrometry. Principles and Applications			Wiley		2007
Gross, J	Mass Spectrometry: a textbook			Springer
Thermo Finnigan	Manual de instrucciones Trace GC Ultra					2003
Thermo Fisher Scientific	Manual de usuario DSQ II					2006
Watson, J; Sparkman, O	Introduction to Mass Spectrometry			Wiley		2007