Guías Docentes Electrónicas
1. General information
Course:
INVESTIGACION EN TOXICOLOGIA APLICADA A LA FAUNA SILVESTRE
Code:
310053
Type:
CORE COURSE
ECTS credits:
6
Degree:
2310 -
Academic year:
2019-20
Center:
601 -
Group(s):
20 
Year:
Sin asignar
Duration:
First quarter
Main language:
Spanish
Second language:
English
Use of additional languages:
English Friendly:
Y
Web site:
Bilingual:
N
Lecturer: RAFAEL MATEO SORIA - Group(s): 20 
Building/Office
Department
Phone number
Email
Office hours
IREC
CIENCIA Y TECNOLOGÍA AGROFORESTAL Y GENÉTICA
6256
rafael.mateo@uclm.es
9:30-12:30

Lecturer: Mª DOLORS VIDAL ROIG - Group(s): 20 
Building/Office
Department
Phone number
Email
Office hours
Facultad de Medicina/1.31
CIENCIAS MÉDICAS
92629530 ext.3386
mariadolors.vidal@uclm.es
Jueves de 15:30 a 17:30

2. Pre-Requisites

Those general pre-requisites of the Máster. Course special interest for graduates in Chemistry, as well as other established for the Master.

3. Justification in the curriculum, relation to other subjects and to the profession

The studies are planned to form the student in wildlife toxicology, giving the necessary knowledge in this subject to develop the research tasks.


4. Degree competences achieved in this course
Course competences
Code Description
E01
E02
E04
E05
E06
E07
E08
G01
G02
G04
G05
G06
G07
G08
G09
G10
5. Objectives or Learning Outcomes
Course learning outcomes
Description
Additional outcomes
Not established.
6. Units / Contents
  • Unit 1: Introduction to toxicology: Definition and types of toxic. Dose-response relationship: types of toxicity. Routes of exposure. Absorption. Metabolism. Excretion. Toxicokinetics Bioaccumulation and biomagnification.
  • Unit 2: Biomarkers Definition of biomarker. Biomarkers of effect and exposure. Types of biomarkers of effect: specific and general.
  • Unit 3: Analytical techniques in toxicology: extraction and purification of organic and inorganic compounds, chromatography, UV-Vis spectrophotometry, absorption and atomic emission, mass spectrometry.
  • Unit 4: Agricultural management and biodiversity conservation. Indirect effects of pesticides. Population trends of wild birds.
  • Unit 5: Direct effects of agrochemicals. Pesticides: anticholinesterase insecticides, anticoagulant rodenticides, fungicides and herbicides. Fertilizers: Nitrates.
  • Unit 6: Problem of the use of poison. Origin, types of poison, diagnosis, actions.
  • Unit 7: Persistent organic pollutants Organochlorine pesticides. PCBs. Dioxins and furans. Endocrine disruption
  • Unit 8: Emerging contaminants: diphenyl polybrominated, polyfluorinated, nanomaterial ethers.
  • Unit 9: Oil pollution in the marine environment. Polycyclic aromatic hydrocarbons. Adverse effects in seabirds.
  • Unit 10: Plumbing in wild birds. Exhibition in waterfowl, land and raptors. Adverse effects of lead. Alternatives to lead ammunition.
  • Unit 11: Contamination by other heavy metals and metalloids: mercury, cadmium, arsenic, selenium.
  • Unit 12: Veterinary drugs: adverse effects on scavenger species. Diclofenac in Asian vultures, other anti-inflammatories and antibiotics.
  • Unit 13: Toxins Toxiinfections food. Botulism. Cyanobacterial toxins: microcystins and other types. Mycotoxins
  • Unit 14: Biomarkers Determination of cerebral acetylcholinesterase activity in animals exposed to organophosphates and carbamates. In vitro reactivation techniques of enzymatic activity.
  • Unit 15: Analytical Toxicology Analysis of pesticides and poisons: solvent extraction, purification by gel permeation chromatography and analysis by gas chromatography coupled to mass spectrometry.
  • Unit 16: Analytical toxicology: Determination of anticoagulant rodenticides
  • Unit 17: Analytical Toxicology Heavy metal analysis: microwave oven digestion and atomic absorption analysis in graphite chamber.
  • Unit 18: Field study
  • Unit 19: Experimental design.
  • Unit 20: Self Learning and Evaluation
7. Activities, Units/Modules and Methodology
Training Activity Methodology Related Competences ECTS Hours As Com R Description
Class Attendance (theory) [ON-SITE] Lectures E01 E02 G01 G04 G08 0.8 20 Y Y Y
Laboratory practice or sessions [ON-SITE] Practical or hands-on activities E04 E05 G01 G04 G08 0.8 20 Y Y Y
In-class Debates and forums [ON-SITE] Projects based learning E02 G02 G04 G05 0.06 1.5 Y N Y
Writing of reports or projects [OFF-SITE] Reading and Analysis of Reviews and Articles E01 E02 E06 G01 G04 G08 1.2 30 Y N Y
Group tutoring sessions [ON-SITE] Group tutoring sessions E08 G04 G06 G09 0.2 5 Y N Y
Writing of reports or projects [OFF-SITE] Project/Problem Based Learning (PBL) E02 E06 E07 G02 G05 G08 1.2 30 Y N Y
Problem solving and/or case studies [ON-SITE] Group Work E02 E06 E07 G01 G02 G04 G05 G06 G07 G08 G09 G10 0.5 12.5 Y N Y
Study and Exam Preparation [OFF-SITE] Self-study E02 E04 E06 G01 G04 G08 1.2 30 Y N Y
Final test [ON-SITE] Problem solving and exercises E01 E02 E04 E05 E06 E07 E08 G01 G02 G04 G05 G06 G07 G08 G09 G10 0.04 1 Y N Y
Total: 6 150
Total credits of in-class work: 2.4 Total class time hours: 60
Total credits of out of class work: 3.6 Total hours of out of class work: 90
As: Assessable training activity
Com: Training activity of compulsory overcoming
R: Rescheduling training activity
8. Evaluation criteria and Grading System
  Grading System  
Evaluation System Face-to-Face Self-Study Student Description
Oral presentations assessment 0.00% 100.00%
Final test 100.00% 0.00%
Total: 100.00% 100.00%  

Evaluation criteria for the final exam:
Evaluation criteria not defined
Specifications for the resit/retake exam:
Evaluation criteria not defined
Specifications for the second resit / retake exam:
Evaluation criteria not defined
9. Assignments, course calendar and important dates
Not related to the syllabus/contents
Hours hours

Unit 1 (de 20): Introduction to toxicology: Definition and types of toxic. Dose-response relationship: types of toxicity. Routes of exposure. Absorption. Metabolism. Excretion. Toxicokinetics Bioaccumulation and biomagnification.
Activities Hours
Class Attendance (theory) [PRESENCIAL][Lectures] 1

Unit 2 (de 20): Biomarkers Definition of biomarker. Biomarkers of effect and exposure. Types of biomarkers of effect: specific and general.
Activities Hours
Class Attendance (theory) [PRESENCIAL][Lectures] 2

Unit 3 (de 20): Analytical techniques in toxicology: extraction and purification of organic and inorganic compounds, chromatography, UV-Vis spectrophotometry, absorption and atomic emission, mass spectrometry.
Activities Hours
Class Attendance (theory) [PRESENCIAL][Lectures] 1

Unit 4 (de 20): Agricultural management and biodiversity conservation. Indirect effects of pesticides. Population trends of wild birds.
Activities Hours
Class Attendance (theory) [PRESENCIAL][Lectures] 1

Unit 5 (de 20): Direct effects of agrochemicals. Pesticides: anticholinesterase insecticides, anticoagulant rodenticides, fungicides and herbicides. Fertilizers: Nitrates.
Activities Hours
Class Attendance (theory) [PRESENCIAL][Lectures] 2

Unit 6 (de 20): Problem of the use of poison. Origin, types of poison, diagnosis, actions.
Activities Hours
Class Attendance (theory) [PRESENCIAL][Lectures] 1

Unit 7 (de 20): Persistent organic pollutants Organochlorine pesticides. PCBs. Dioxins and furans. Endocrine disruption
Activities Hours
Class Attendance (theory) [PRESENCIAL][Lectures] 2

Unit 8 (de 20): Emerging contaminants: diphenyl polybrominated, polyfluorinated, nanomaterial ethers.
Activities Hours
Class Attendance (theory) [PRESENCIAL][Lectures] 1

Unit 9 (de 20): Oil pollution in the marine environment. Polycyclic aromatic hydrocarbons. Adverse effects in seabirds.
Activities Hours
Class Attendance (theory) [PRESENCIAL][Lectures] 2

Unit 10 (de 20): Plumbing in wild birds. Exhibition in waterfowl, land and raptors. Adverse effects of lead. Alternatives to lead ammunition.
Activities Hours
Class Attendance (theory) [PRESENCIAL][Lectures] 2

Unit 11 (de 20): Contamination by other heavy metals and metalloids: mercury, cadmium, arsenic, selenium.
Activities Hours
Class Attendance (theory) [PRESENCIAL][Lectures] 2

Unit 12 (de 20): Veterinary drugs: adverse effects on scavenger species. Diclofenac in Asian vultures, other anti-inflammatories and antibiotics.
Activities Hours
Class Attendance (theory) [PRESENCIAL][Lectures] 2

Unit 13 (de 20): Toxins Toxiinfections food. Botulism. Cyanobacterial toxins: microcystins and other types. Mycotoxins
Activities Hours
Laboratory practice or sessions [PRESENCIAL][Practical or hands-on activities] 4

Unit 14 (de 20): Biomarkers Determination of cerebral acetylcholinesterase activity in animals exposed to organophosphates and carbamates. In vitro reactivation techniques of enzymatic activity.
Activities Hours
Laboratory practice or sessions [PRESENCIAL][Practical or hands-on activities] 4

Unit 15 (de 20): Analytical Toxicology Analysis of pesticides and poisons: solvent extraction, purification by gel permeation chromatography and analysis by gas chromatography coupled to mass spectrometry.
Activities Hours
Laboratory practice or sessions [PRESENCIAL][Practical or hands-on activities] 4

Unit 16 (de 20): Analytical toxicology: Determination of anticoagulant rodenticides
Activities Hours
Laboratory practice or sessions [PRESENCIAL][Practical or hands-on activities] 4

Unit 17 (de 20): Analytical Toxicology Heavy metal analysis: microwave oven digestion and atomic absorption analysis in graphite chamber.
Activities Hours
Laboratory practice or sessions [PRESENCIAL][Practical or hands-on activities] 4

Unit 18 (de 20): Field study
Activities Hours
In-class Debates and forums [PRESENCIAL][Projects based learning] 1.5
Writing of reports or projects [AUTÓNOMA][Reading and Analysis of Reviews and Articles] 30
Group tutoring sessions [PRESENCIAL][Group tutoring sessions] 5
Writing of reports or projects [AUTÓNOMA][Project/Problem Based Learning (PBL)] 30
Problem solving and/or case studies [PRESENCIAL][Group Work] 12.5

Unit 19 (de 20): Experimental design.
Activities Hours
Study and Exam Preparation [AUTÓNOMA][Self-study] 30
Final test [PRESENCIAL][Problem solving and exercises] 1

Global activity
Activities hours
10. Bibliography and Sources
Author(s) Title Book/Journal Citv Publishing house ISBN Year Description Link Catálogo biblioteca
 
Beyer, W.N., Meador, J.P. Environmental Contaminants in Biota: Interpreting Tissue Concentrations Boca Raton, FL CRC Pre 2011  
Elliott, J.E., Bishop, C.A., Morrisey, C.A. Wildlife Ecotoxicology: Forensic Approaches Springer 2011  
Hoffman, D.J., Rattner, B.A., Burton G.A., Cairns, J. Handbook of Ecotoxicology Boca Raton, FL Lewis Publishers 2003  
Shore, R.F., Rattner, B.A. Ecotoxicology of Wild Mammals Chichester, UK John Wiley and Sons Ltd 2001  



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